Cardiology Research Institute, Tomsk NRMC
Tomsk, 634012, Russia
NCT Number: NCT03674593
The study compares the efficacies of two surgical procedures for the treatment of mitral valve prolapse due to myxomatous degeneration of the mitral valve: the chordae replacement and the translocation of secondary mitral valve chordae.
This study is active but is not currently recruiting participants.
Notify Me18 year and older
All sexes
Interventional
Not applicable
Tomsk, 634012, Russia
Summary: This study compares the efficacy and the safety of two surgical procedures for the treatment of mitral valve prolapse due to degeneration of the mitral valve: chordae replacement and the translocation of secondary mitral valve chordae.
In our study, researchers used the loop method proposed by von Oppel and Mohr in 2000. The main principle of the method of prosthetic chordae is the preservation of the native anatomy of the mitral valve. This principle is achieved by the implantation of artificial chordae made of ePTFE Gore-Tex threads.
The chordae replacement method essentially involves five stages:
Chordae translocation is the alternative method, which does not require measurement and selection of chordae lengths. Chordae replacement is technically easier (less aortic clamping time) with comparable results.
The technique of translocation of secondary chordae essentially consists of three stages:
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
The method consists of five stages:
Other names: Chordae prosthesis
The method consists essentially of three stages:
Other names: Chordae translocation
Time frame: Two weeks
Mitral regurgitation degree (from 1 to 4) assessed by echocardiography two weeks after surgery
Time frame: One year
Mitral regurgitation degree (from 1 to 4) assessed by echocardiography one year after surgery
Time frame: Two weeks
Effective regurgitant orifice (ERO) (in square millimeters) assessed by echocardiography two weeks after surgery
Tomsk National Research Medical Center of the Russian Academy of Sciences
Other
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