Skip to main content
OpenTrials
Completed

NCT Number: NCT01575158

Citalopram vs Clomipramine vs Placebo in Recurrent Depression

citalopram and clomipramine are better than placebo in preventing new episodes of depression in patients with recurrent depression

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Depression Behavior Behavioral Symptoms

Age range

18 year–70 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients with recurrent depression
  • Sustained response achieved (3 consecutive monthly ratings at the HDS below 13)after a treatment requiring index episode

Exclusion criteria

  • Contraindications to study medications
  • Pregnancy
  • Substance abuse

Treatment and study plan

Citalopram

Drug

Clomipramine

Drug

Placebo

Drug

Primary outcomes

  1. 2 Hamilton Depression Rating Scale scores of at least 16 with one weeks interval or initiation of another antidepressant treatment

    Time frame: 2 years of follow-up

Secondary outcomes

  1. Study termination due to adverse event or non-compliance

    Time frame: 2 years of follow-up

Sponsors and collaborators

Lead sponsor

University of Aarhus

Other

Collaborators

  • Danish University Antidepressant Group

Registry information

Important dates

Study start
1997
Primary completion
2007
Study completion
2007
First posted
Apr 11, 2012
Registry last updated
Apr 11, 2012

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.