Cervical Spine Abnormalities in Down Syndrome

The study aims to determine the prevalence,clinical presentations and radiographic cervical spine abnormalities associated Down syndrome in children at sohag university hospital

Active, Not Recruiting

This study is active but is not currently recruiting participants.

Key information

Conditions

Down Syndrome Abnormalities, Multiple Cervical Spine Instability in Down Syndrome Chromosome Disorders Congenital Abnormalities Congenital, Hereditary, and Neonatal Diseases and Abnormalities Genetic Diseases, Inborn Intellectual Disability Nervous System Diseases Neurobehavioral Manifestations Neurologic Manifestations

Age range

2 year–18 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Sohag university hospital

Sohag, Egypt

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

All patients attending to pediatric inpatient and outpatient clinics aged from 2y up to 18 y

Exclusion criteria

children with other clinical syndromes Children with other neurological disorders (eg. Cerebral palsy , myopathy, neuropathy

Treatment and study plan

Primary outcomes

Determine the prevalence, clinical presentations and radiographic cervical spine abnormalities associated with Down syndrome through study completion an average of 1 year .

Time frame: Asses the perivlance of cervical spine abnormalities in patient with Down syndrome of patients aged from 2 years up to 18 years ,using measure tool atlanoaxial instability in ct neck (ADI>3ml)and other mutliple measures ex(weight,height,eg.)

Sponsors and collaborators

Lead sponsor

Sohag University

Other

Registry information

Official study title

A Study of Cervical Spine Abnormalities Associated With Down Syndrome in Children at Sohag University

Important dates

Study start: 2025
Primary completion: 2026
Study completion: 2026
First posted: Dec 3, 2025
Registry last updated: Dec 3, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Active, Not Recruiting