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Completed

NCT Number: NCT06399913

Cerebral Computed Tomography on Patients With Minor Head Injuries

This observational study aims to calculate the prevalence of conditions or diseases requiring immediate medical attention in CTC scans with an indication of bleeding post trauma performed in the ED at Odense University Hospital. Secondary, we aim to evaluate the Scandinavian Neurotrauma Committee clinical guideline 2013 for minor head injury.

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Key information

About this study

In this retrospective study, our primary objectives are threefold: first, to calculate the prevalence of conditions or diseases requiring immediate medical attention and to subdivide them to explore potential correlations with biochemical, clinical, and patient baseline variables using multiple regression analysis. Secondly, we wanted to analyze our use of SNC CPG and evaluate if a more stringent application could reduce the potentially unnecessary overuse of CTC. Lastly, we aim to evaluate the 30-day mortality and readmission rates to a hospital following CTC performed in the ED.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • CTCs conducted from 01.01.2023 to 31.12.2023 in the ED

Exclusion criteria

  • unrelated to trauma
  • scans performed on patients under the age of 18
  • CTC scans without radiologic interpretation
  • Previously undergone a CTC during the same hospitalization, only the first CTC was included

Treatment and study plan

Primary outcomes

  1. Positive CTC

    Time frame: 1 year

    Calculate the prevalence of positive CTC findings and to subdivide them to explore potential correlations with biochemical, clinical, and patient baseline variables.

    The CT scan was acknowledged as positive if the final radiologic interpretation of all imaging studies reported one or more listed radiological findings:

    • Epidural hematoma
    • Subdural hematoma
    • Subarachnoid hematoma
    • Intraparenchymal hematoma (IPH)
    • Intraventricular hematoma
    • Fossa posterior hematoma
    • Acute infarct or dense artery sign
    • Mass effect or sulcal effacement
    • Signs of herniation
    • Basal cistern compression or midline shift
    • Cerebral contusion
    • Depressed skull fracture
    • Diastatic skull fracture
    • Pneumocephalus
    • Cerebral edema
    • Diffuse axonal injury
    • Tumor
    • Intracranial infection
    • Other which resulted in hospitalization

Secondary outcomes

  1. Scandinavian Neurotrauma Committee clinical practice guideline evaluation

    Time frame: 1 year

    We wanted to analyze our use of SNC CPG and evaluate if a more stringent application could reduce the potentially unnecessary overuse of CTC

Other outcomes

  1. 30-day mortality and readmission rate

    Time frame: 1 year

    We aim to evaluate the 30-day mortality and readmission rates to a hospital following CTC performed in the ED.

  2. Neurological intervention

    Time frame: 1 year

    The need for neurological intervention was defined as within 7 days requiring 1) neurosurgical intervention (e.g., craniotomy, hematoma evacuation, elevation of skull fracture, intracranial pressure monitoring, or intubation for head injuries indicated on CT) or 2) neuroradiological intervention (e.g., thrombectomy or intravascular embolization).

Sponsors and collaborators

Lead sponsor

University of Southern Denmark

Other

Registry information

Official study title

Use of Cerebral Computed Tomography on Patients With Minor Head Injuries in a Danish Emergency Department: A Retrospective Cohort Study

Important dates

Study start
2023
Primary completion
2023
Study completion
2024
First posted
May 6, 2024
Registry last updated
May 6, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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