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Completed

NCT Number: NCT06845462

Application of Artificial Intelligence Algorithm Based on CT Imaging for Muscle Parameter Measurement

To establish an artificial intelligence model for automated diagnosis of sarcopenia based on CT imaging

Completed

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Key information

Age range

18 year–90 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Shanghai Jiaotong University School of Medicine, Renji Hospital Ethics Committee

Shanghai, Shanghai Municipality, 2000127, China

About this study

With the accelerating aging process, the early identification and diagnosis of sarcopenia, along with the effective prevention of its adverse outcomes, have become a focal point in medical research. However, current methods for assessing and diagnosing sarcopenia still face significant limitations, making the development of more efficient and accurate techniques for muscle mass evaluation an urgent clinical need. Although CT is considered as the most promising method for assessing muscle mass, its practical application is hindered by factors such as reliance on physician expertise and time-consuming procedures, limiting its widespread clinical adoption. In light of these challenges, this study aims to develop an artificial intelligence model for fully automated muscle mass measurement based on abdominal CT imaging and to validate its application value in assisting the diagnosis of sarcopenia.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • The population undergoing BIA and abdominal CT examinations;
  • Can cooperate to complete human body composition analysis, grip strength measurement, 6m walking time measurement, and questionnaire survey.

Exclusion criteria

  • Age<18 years old;
  • Existence of abdominal wall edema;
  • History of spinal surgery or vertebral fractures, or vertebral tumor lesions;
  • History of neuromuscular disorders.

Treatment and study plan

Primary outcomes

  1. To automatedly and precisely quantify three-dimensional muscle volume and fat volume.

    Time frame: 2020-2023

    To achieve an automated and precise quantification of three-dimensional muscle volume and fat volume at the L3 vertebral region by deep learning.

  2. To establish an artificial intelligence model for diagnosis of sarcopenia.

    Time frame: 2020-2023

    The validation of artificial intelligence models can assist in the diagnosis of sarcopenia.

Sponsors and collaborators

Lead sponsor

RenJi Hospital

Other

Registry information

Official study title

Application of Artificial Intelligence Algorithm Based on CT Imaging for Muscle Parameter Measurement in the Diagnosis of Sarcopenia

Important dates

Study start
2023
Primary completion
2024
Study completion
2024
First posted
Feb 25, 2025
Registry last updated
Feb 25, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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