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OpenTrials
Completed

NCT Number: NCT02125942

Central Meditation and Imagery Therapy for Augmentation of Borderline Personality Disorder Treatment

Borderline personality disorder is a severe psychiatric disorder marked by emotional instability, difficulty with interpersonal relationships, and self-harming behaviors. Despite receiving psychotherapy for borderline personality disorder, studies show that patient recovery is slow, and there is a high rate of self injury and suicide attempts early in treatment. There is thus a clear need to provide therapies to augment psychotherapy. We will conduct a pilot trial to determine whether a 6-week Central Meditation and Imagery Therapy (CMIT) is feasible for subjects with borderline personality disorder to undergo when added on to psychotherapy treatment. CMIT is a non-validated therapy that combines principles of mindfulness with meditation techniques and guided imagery. Sessions led by a trained clinician in a group setting once a week, and participants are asked to complete daily home practice.

The trial will involve 16 participants, all currently undergoing psychotherapy for borderline personality disorder. Participants will be randomly assigned to either a CMIT group that lasts 6 weeks, or a wait list group. Those in the wait list group will be able to receive CMIT after 6 weeks. All participants will continue to receive psychotherapy throughout the trial.

During the trial, we will also obtain preliminary data to help understand whether CMIT may result in psychological benefits for participants. This will include measuring the pulse in order to determine variation in beat to beat intervals of the heart during psychological tests, and filling out questionnaires before and after participation in CMIT.

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

University of California, Los Angeles

Los Angeles, California, 90095, United States

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Meeting the diagnostic criteria for BPD according to DSM-IV criteria
  • Meeting the diagnostic criteria for BPD based on the Diagnostic Interview for Borderline - Revised
  • Currently receiving psychotherapy.
  • English language proficiency to understand written and oral communication

Exclusion criteria

  • Active suicidality or suicidal intent as identified on the Columbia Suicide Severity Rating Scale
  • Suicide attempt within the past month

Treatment and study plan

Central Meditation and Imagery Therapy

Behavioral

mindfulness, guided imagery, meditation

Primary outcomes

  1. Borderline Symptoms

    Time frame: 6 weeks

    Borderline Symptom List

Secondary outcomes

  1. Depression

    Time frame: 6 weeks

    Quick Inventory of Depressive Symptoms

  2. Anxiety

    Time frame: 6 weeks

    Trait Anxiety Inventory

  3. Positive Affect

    Time frame: 6 weeks

    Positive and Negative Affect Scale

Other outcomes

  1. Heart rate variability

    Time frame: 6 weeks

    Resting heart rate variability

Sponsors and collaborators

Lead sponsor

University of California, San Francisco

Other

Registry information

Official study title

Pilot Study of Central Meditation and Imagery Therapy for Borderline Personality Disorder

Important dates

Study start
2014
Primary completion
2015
Study completion
2015
First posted
Apr 29, 2014
Registry last updated
Jan 13, 2021

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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