Carotid Atherosclerosis in Patients With Aortic Coarctation

Despite aortic coarctation (CoA) repair these patients have cardiovascular complications and coronary artery disease is the most common cause of death.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Atherosclerosis Aortic Coarctation Arterial Occlusive Diseases Arteriosclerosis Cardiovascular Abnormalities Cardiovascular Diseases Congenital Abnormalities Congenital, Hereditary, and Neonatal Diseases and Abnormalities Heart Defects, Congenital Heart Diseases Vascular Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

About this study

The aim with this study was to measure intima-media thickness (IMT) and plaques in arteries compared to cardiovascular markers in controls and patients with CoA.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

sex and age-matched controls

Exclusion criteria

acute and chronic inflammation disease, underlying malignancies and diabetes mellitus.

Treatment and study plan

Ultrasound measurement

Other

Ultrasound measurement

Primary outcomes

Intima-media thickness

Time frame: Intima-media thickness will be measured at one time point namely at inclusion. Data will be reported when study is completed, an average of 2 year.

Measurement in mm

Secondary outcomes

Cardiovascular markers

Time frame: Blood samples will be taken at one time point namely at inclusion. Then biomarkers will be analysed when study is completed. Data will be reported when study is completed, an average of 2 year.

A multiplex platform to analyze circulating blood levels biomarkers was used.

Sponsors and collaborators

Lead sponsor

Skane University Hospital

Other

Registry information

Acronym: CoA

Important dates

Study start: 2012
Primary completion: 2019
Study completion: 2019
First posted: Jun 26, 2019
Registry last updated: Jun 26, 2019

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed