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OpenTrials
Completed

NCT Number: NCT06087250

Carotid Artery Corrected Flow Time and Fluid Responsiveness in Geriatric Patients

Carotid blood flow and corrected carotid flow time (Carotid Flow Time (FTc)) provide information about left ventricular preload and inversely correlate with systemic vascular resistance. The reliability in assessing fluid responsiveness has been demonstrated in studies involving invasive cardiac output measurements. In the elderly patient population where arterial elasticity can be compromised, there is no existing data in literature that determines the reliability and predictive value of FTc after general anesthesia induction.

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Key information

Conditions

Fluid Responsiveness Common Carotid Artery

Age range

65 year–100 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Marmara University Hospital

Istanbul, Turkey (Türkiye)

About this study

Doppler ultrasound of the common carotid artery has begun to be used as a potential non-invasive tool for assessing hemodynamic status. Its non-invasive nature, ability to be applied independently of the patient's position, ease of application due to the superficial location of the carotid artery, and resistance to intrathoracic pressure changes are among its advantages. Carotid blood flow and corrected carotid flow time (Carotid Flow Time (FTc)) provide information about left ventricular preload and inversely correlate with systemic vascular resistance. Additionally, the velocity time integral (VTI) measuring blood flow through the carotid artery during systole, when multiplied by the cross-sectional area of the carotid artery, allows for the determination of flow within the carotid artery. The reliability in assessing fluid responsiveness has been demonstrated in studies involving invasive cardiac output measurements. In the elderly patient population where arterial elasticity can be compromised, there is no existing data in literature that determines the reliability and predictive value of FTc after general anesthesia induction.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • geriatric patient (older than 65 years of age) having surgery under general anesthesia

Exclusion criteria

  • Common carotid artery stenosis, common carotid artery disease

Treatment and study plan

Primary outcomes

  1. carotid corrected flow time (cFT)

    Time frame: 1 hour

    the ability ofc FT to predict fluid responsiveness

Secondary outcomes

  1. cutt-of value of cFT

    Time frame: 1 hour

    the cutt-of value of cFT to predict fluid responsiveness

Sponsors and collaborators

Lead sponsor

Marmara University

Other

Registry information

Official study title

Reliability of Carotid Artery Corrected Flow Time Predicting Fluid Responsiveness in Geriatric Patients.

Important dates

Study start
2023
Primary completion
2023
Study completion
2023
First posted
Oct 17, 2023
Registry last updated
Apr 2, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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