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NCT Number: NCT07725757

Caries of First Permanent Molars and Association With Dietary and Oral Habits Among a Group of Egyptian Children

This cross-sectional study aims to assess the prevalence of dental caries in the first permanent molars of Egyptian children aged 6 to 7 years, and to examine how this caries status relates to the children's dietary habits and oral hygiene practices. A total of 272 children will undergo a clinical oral examination, and their parents or guardians will complete a structured questionnaire covering diet, tooth-brushing habits, and socio-demographic background. The findings are intended to help identify risk factors associated with early caries in these key teeth, supporting better-targeted preventive dental care for this age group.

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Key information

Age range

6 year–7 year

Sex eligibility

All sexes

Study type

Observational

About this study

First permanent molars are the earliest-erupting permanent teeth and, because they emerge without replacing a primary tooth, they are particularly susceptible to plaque accumulation and early carious lesions. As they account for a large proportion of dental caries in school-aged children, their eruption period represents a critical window for preventive interventions such as pit-and-fissure sealants.

Dental caries remains one of the most prevalent chronic diseases in childhood worldwide, with a multifactorial etiology involving diet, sugar consumption, salivary factors, fluoride exposure, and oral hygiene behavior. In Egypt, population-level data on the caries status of first permanent molars specifically - as opposed to caries in the dentition generally - remain limited.

This study will use a cross-sectional observational design conducted in the Paediatric Dentistry Department at October University for Modern Sciences and Arts (Giza, Egypt). Children aged 6-7 years who meet the eligibility criteria (healthy, no history of radiotherapy/chemotherapy, no retained primary teeth or developmental anomalies affecting the permanent dentition, no orthodontic treatment, and provision of parental informed consent) will be enrolled.

Each participating child will receive an intraoral clinical examination using a mirror and CPI probe, following WHO Oral Health Survey (2013) criteria, to assess caries status of the first permanent molars using the DMFT index and to record eruption pattern. Parents/guardians will complete a pre-tested, structured questionnaire (translated into Arabic) capturing dietary habits, tooth-brushing frequency, flossing, sweets intake, dental check-up frequency, fluoride toothpaste use, and socio-demographic variables (child's sex, number of children in the family, parental education).

Based on a previously reported FPM caries prevalence of 5.5%, a sample size of 272 children was calculated (97% confidence interval, 3% margin of error, with finite population correction, using Epi Info v7.2.5.0)

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age: 6 to 7 years old children
  • Children with written informed consent from their parents or guardians were included
  • Healthy child

Exclusion criteria

  • Previous history/current radiotherapy and/or chemotherapy.
  • Presence of retained primary teeth or congenital or developmental anomalies affecting the permanent dentition.
  • Missing teeth due to causes other than dental caries.
  • Subjects undergoing orthodontic therapy, which might preclude normal tooth brushing.
  • Subjects who, in the opinion of the Investigator, may be non-compliant with study procedures.

Treatment and study plan

Primary outcomes

  1. DMFT

    Time frame: baseline

    Measuring DMFT index for first permanent molars

Secondary outcomes

  1. DMFS

    Time frame: baseline

    Measuring DMFS index for first permanent molar

  2. Oral hygiene habits

    Time frame: baseline

    Assessing oral hygiene habits through questionnaire for children aged 6-7 years

  3. Dietary habits

    Time frame: baseline

    Measuring Dietary habits through questionnaire for children aged 6-7 years

Study contacts

Contact information is provided by the study sponsor or research team.

Noor Mohamed Hanafy, General Dentist

CONTACT

[email protected]

00201033475613

Sponsors and collaborators

Lead sponsor

October University for Modern Sciences and Arts

Other

Registry information

Official study title

Caries Status of First Permanent Molars and Their Association With Dietary and Oral Hygiene Habits Among a Group of Egyptian Children Aged 6-7 Years : A Cross Sectional Study.

Important dates

Study start
2026
Primary completion
2026
Study completion
2026
First posted
Jul 24, 2026
Registry last updated
Jul 24, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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