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OpenTrials
Completed

NCT Number: NCT00604149

Cardiac AResT And GENEtic

Sudden death is a major problem in industrially developed countries. Despite a decline in ischemic heart disease mortality and the progress has been made in resuscitation, treatment of sudden death victims is frequently unsuccessful. the ideal solution would be to prevent the disease process that causes the initial episode of cardiac arrest. Parental sudden death is an independent risk factor for sudden death. So, detect a gene predisposing to sudden death may help provide better identification of subjects at high risk of cardiac arrest. This research is a genetic study of sudden cardiac death, recruited 2000 subjects in out-of-hospital cardiac arrest.

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Key information

Age range

18 year–75 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Hôpital Européen Georges Pompidou

Paris, 75015, France

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • OHCA
  • Aged from 18 to 75 years

Exclusion criteria

  • Pregnant
  • People not free
  • Inhospital subjects
  • Death by other disease
  • Violent death

Treatment and study plan

Primary outcomes

  1. Frequency of Single Nucleotide Polymorphism (SNP) across the entire genome

    Time frame: Day 1

    DNA extracted from blood cells

Sponsors and collaborators

Lead sponsor

Institut National de la Santé Et de la Recherche Médicale, France

Other Gov

Registry information

Official study title

Etude Multicentrique en Population de la susceptibilité génétique à Faire Une Mort Subite

Acronym: CARTAGENE

Important dates

Study start
2008
Primary completion
2014
Study completion
2014
First posted
Jan 30, 2008
Registry last updated
Feb 18, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.