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OpenTrials
Completed

NCT Number: NCT06858943

Can Tendon Autograft Function As a Meniscal Transplant

Purpose: To evaluate the functional outcomes after using peroneus longus (PL) tendon autograft as meniscal transplantation in patients with knee joint line pain exaggerated with weight bearing following prior total or subtotal meniscectomy.

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Key information

Conditions

Meniscectomy

Age range

22 year–40 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Faculty of Medicine, Cairo University

Giza, Cairo Governorate, Egypt

About this study

This research design is a single center prospective study carried out at a tertiary trauma center hospital between May 2022 and December 2022. This research had ethical Committee Approval which was granted by the Ethics Committee of Cairo University (Institutional Review Board (IRB) number N 207-2024). All patients signed an informed consent before joining this study. This study included 25 patients, with previous history of subtotal or total meniscectomy medially or laterally, who underwent meniscus transplantation using PL tendon autograft.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Skeletally mature patients with a history of prior subtotal or total (medial or lateral meniscus) meniscectomy.
  • Post meniscectomy symptoms (medial or lateral knee joint line pain exaggerated with weight bearing).

Exclusion criteria

  • Multi-ligamentous knee injuries.
  • Skeletally immature patients.
  • Significant osteoarthritic changes on radiographs (Ahlbäck II- V).
  • Malalignment on full-length radiographs showing increased stress in the involved knee compartment.
  • Presence of associated ipsilateral ankle joint problem.

Treatment and study plan

arthroscopic meniscus reconstruction using a tendon autograft

Procedure

arthroscopic meniscus reconstruction using a tendon autograft

Primary outcomes

  1. Lysholm knee score

    Time frame: baseline, 2 years postoperative

    functional knee score, minimum is zero, maximum value is 100, a higher score means a better outcome

  2. Knee Injury and Osteoarthritis and Outcome (KOOS) score

    Time frame: baseline, and 2 years postoperative

    osteoarthritis knee score, minimum is zero, maximum is 100, higher score means a better outcome

Sponsors and collaborators

Lead sponsor

Cairo University

Other

Registry information

Acronym: DR

Important dates

Study start
2022
Primary completion
2024
Study completion
2024
First posted
Mar 5, 2025
Registry last updated
Mar 11, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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