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NCT Number: NCT01591226

Caffeine and Sodium Citrate Ingestion

A positive ergogenic effect of sodium citrate and caffeine ingestion in a short-term, high-intensity exercise task was shown by several studies. These studies were conducted with healthy, able-bodied subjects.

The aim of the study is to investigate whether caffeine or sodium citrate ingestion could enhance performance in spinal cord injured wheelchair athletes. It is a double blind, placebo controlled and randomized study.

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Key information

Conditions

Dietary Supplements Heart Rate/Drug Effects Lactic Acid/Metabolism Physical Education and Training/Methods Wheelchairs

Age range

18 year–55 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Swiss Paraplegic Centre

Nottwil, Canton of Lucerne, 6207, Switzerland

About this study

The athletes have to complete four 1500m tests on a training roller. Before each treatment they get different supplementations. Once they get sodium citrate and a placebo, once caffeine and a placebo, once sodium citrate and caffeine and for the fourth treatment they get twice a placebo. Two hours after starting with the supplementation they have to complete the 1500m as fast as possible. Time to complete 1500m, blood pH, plasma bicarbonate, sodium concentration, heart rate, oxygen consumption, blood lactate concentration and rate of perceived exertion (RPE) were measured.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • wheelchair athletes
  • national team
  • category T53 and T54

Exclusion criteria

  • medicated
  • pregnant (for women)
  • cardiovascular and respiratory diseases

Treatment and study plan

Caffeine

Dietary Supplement

gelatine capsule 6mg/kg bodyweight 60min prior test

Sodium Citrate

Dietary Supplement

0.5g/kg bodyweight diluted in 7dl water ingested 120-90min prior test

Mannitol

Dietary Supplement

gelatine capsule filled with mannitol (100mg per capsule) ingested 60min prior test

Sodium chloride

Dietary Supplement

sodium chloride diluted in 7dl water 0.045g/kg bodyweight 120-90min prior test

Primary outcomes

  1. Time

    Time frame: 3 weeks

    Time to complete 1500m

Secondary outcomes

  1. Heart Rate

    Time frame: during study phase of 3 week (4 tests)

    Heart Rate measured from 2min before the test until 5min after the 1500m-test.

  2. Lactate Concentration

    Time frame: during the 3 weeks study phase

    1min before starting the warm up, 15s after the end of the warm up, 15s after completing the test, 2min/4min/6min/8min/10min after the test

  3. blood pH, sodium concentration and plasma bicarbonate

    Time frame: during the 3 weeks of study phase

    1min before starting with the ingestion of the fluid, immediately before starting the warm up, just immediately before starting the 1500m test.

  4. Oxygen Consumption

    Time frame: during 3 weeks of study phase

    oxygen consumption (VO2(ml/min/kg), VCO2(ml/min), RER (VCO2/VO2)) starting of the measurement is 2min before the start of the 1500m and ends 2min after having completed the 1500m

  5. rating of gastrointestinal stress

    Time frame: during the 3 weeks of study phase

    1min before starting to drink the fluid, 2min before starting with the warm up, 2min before the test and 2min after having completed the 1500m

  6. Rating of Perceived Exertion (RPE)

    Time frame: during the 3 weeks of study phase

    15s after the end of the warm up, 15s after having completed the 1500m

Sponsors and collaborators

Lead sponsor

Swiss Paraplegic Research, Nottwil

Network

Registry information

Official study title

Effects of Caffeine and Sodium Citrate Ingestion in 1500m Wheelchair Racing Athletes

Important dates

Study start
2012
Primary completion
2012
Study completion
2012
First posted
May 3, 2012
Registry last updated
Nov 22, 2016

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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