Bronchi Dilation in Polynesian Patients: Monocentric Retrospective Study

The study hypothesis is that dilations of idiopathic bronchi are particularly common in French Polynesia, and that there are arguments in favour of an underlying genetic factor.

The study will retrieve retrospective data in the history of bronchial dilation, patients' personal and family history, microbiological and scannographic data, and the latest cardio respiratory checkup.

Recruiting

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Key information

Conditions

Polynesian Bronchiectasis Abnormalities, Multiple Bronchial Diseases Bronchiectasis Cardiovascular Abnormalities Cardiovascular Diseases Ciliary Motility Disorders Ciliopathies Congenital Abnormalities Congenital, Hereditary, and Neonatal Diseases and Abnormalities Dextrocardia Genetic Diseases, Inborn Heart Defects, Congenital Heart Diseases Kartagener Syndrome Otorhinolaryngologic Diseases Respiratory System Abnormalities Respiratory Tract Diseases Situs Inversus

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

CH Polynésie Francaise

Papeete, French Polynesia

Location status: Recruiting

Location contact

Eric PARRAT, MD

CONTACT

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Polynesian patient
Patient with bronchial dilation followed by Centre hospitalier de Polynesie Francaise or patient with bonchial dilation no longer consulting in the hospital over the study period Jan 1, 2010 to Dec 31, 2020

Exclusion criteria

Expressed refusal to participate in the study for patients undergoing follow-up

Treatment and study plan

Primary outcomes

Describe the detailed phenotype of bronchi dilation in the Polynesian population

Time frame: Day 1
- Clinical criteria: age of onset, personal or family history, smoking Changes in respiratory function
- Infectious complications: types of bronchial colonization (bacterial, mycobacterial and mycological)
- Scantographic aspect: Appearance of bronchectasis: cylindrical, varicose orcious, cystic Distributions: LSD, LM, LID, LSG, LIG

Secondary outcomes

Highlighting indirect arguments for a genetic cause

Time frame: Day 1

Age of onset of symptoms, frequency of so-called "idiopathic" bronchi dilatation, frequency of inbreeding, familial history

Study contacts

Contact information is provided by the study sponsor or research team.

Benoit Douvry, MD

CONTACT

[email protected]

01 45 17 57 28

Eric PARRAT, MD

CONTACT

[email protected]

00 689 87707790

Sponsors and collaborators

Lead sponsor

Centre Hospitalier Intercommunal Creteil

Other

Registry information

Important dates

Study start: 2025
Primary completion: 2025
Study completion: 2027
First posted: Mar 16, 2021
Registry last updated: Jun 15, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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Recruiting