Medical University of South Carolina Institute of Psychiatry Senior Care Unit
Charleston, South Carolina, 29425, United States
NCT Number: NCT07002554
Bright light therapy has been shown to be effective for the treatment of both seasonal and non-seasonal unipolar depression as well as bipolar depression, primarily in outpatients under the age of 60. There is a dearth of studies exploring the efficacy of this treatment modality among elderly depressed inpatients, which is our study population.
Interested in participating?
Request Info60 year and older
All sexes
Interventional
Phase 2
Charleston, South Carolina, 29425, United States
Investigators are studying the ability of light therapy to reduce depressive symptoms in elderly patients who are hospitalized with unipolar depression (depression that is not due to bipolar disorder). Participants will receive either active light treatment or inactive treatment (also known as placebo).
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
the Verilux® HappyLight® Lumi Plus light therapy box, which delivers UV-free, full-spectrum LED light at an intensity of 10,000 lux
Other names: light therapy
The control group will use the same light box device, configured to emit dim red light. This will be achieved by setting the box to its lowest brightness setting and overlaying a translucent red filter over the light display. This setup is intended to maintain the appearance and experience of light exposure while minimizing any therapeutic effect.
Time frame: Up to week 6 (Upon time of discharge from inpatient unit)
Percentage of patients who complete the study while psychiatrically hospitalized
Time frame: Up to week 6 (Upon time of discharge from inpatient unit)
assessed by the proportion of participants who correctly identify their study arm allocation. Blinding will be considered adequate if the proportion of correct guesses does not significantly exceed chance levels
Time frame: Day of enrollment, week 1, week 2, week 4, week 6
HAMD-17 is a commonly used clinician rating scale for depressive symptoms
Time frame: Day of enrollment, week 1, week 2, week 4, week 6
BDI-II is a commonly used self-report rating scale for depressive symptoms
Medical University of South Carolina
Other
The LIGHT-60 Trial - Light Intervention for Geriatric Patients Hospitalized for Depression Treatment
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
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