Breast MRI Screening in Women Treated With Mediastinal Irradiation for Hodgkin's Disease

• The screening breast MRI and mammography will be performed 6 months or longer after the last mammogram. For pre-menopausal women, the screening will be performed during the second week of the menstrual cycle to reduce cycle-related breast changes. As much as possible, the breast MRI and mammogram are to be performed on the same day.
• On the day of the breast imaging studies, the patient will also be asked to fill out a baseline breast health questionnaire, which includes questions on time since radiation therapy, prior screening history, history of prior benign breast biopsies, menopausal status, prior hormonal therapy use, etc.
• In patients with suspicious findings or findings highly suggestive of malignancy, the abnormal findings will be reviewed with the patient and recommendations will be made for a biopsy.

Inclusion criteria

• Female patients treated with radiation therapy to the chest area for Hodgkin's disease
• Age between 12 and 35 at initial treatment
• Eight years or longer after initial treatment
• Pre-approval from the participant's insurance company for the breast imaging studies

Exclusion criteria

• Pregnant or lactating women
• Post Bilateral mastectomy
• Currently undergoing breast cancer therapy
• Known metastatic cancer
• Patients with contraindications for undergoing an MRI: cardiac pacemaker, known metallic objects in body e.g. metallic clips, bullets, shrapnel or buckshots.