Bone Structure and Strength Evaluated by Extreme-CT Scan Before and After Treatment of Hyper- and Hypothyroidism

The aim to evaluate the bone structure by Dexa-scan, extreme CT and bone markers before and one year after treatment for a thyroid functional disorder

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Key information

Conditions

Hyperthyroidism Bone Diseases Bone Diseases, Metabolic Endocrine System Diseases Hypothyroidism Metabolic Diseases Musculoskeletal Diseases Nutritional and Metabolic Diseases Osteoporosis Thyroid Diseases

Age range

18 year–85 year

Sex eligibility

Female

Study type

Observational

Primary location

Odense University Hospital

Odense, 5000, Denmark

About this study

The aim to evaluate the bone structure by Dexa-scan, extreme CT and bone markers before and one year after treatment for a thyroid functional disorder. Women with hyper- og hypothyroidism are included and undergo usual treatment. Patients are stratified into 10 different groups.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

informed consent, female sex, age 20-85 years, indication for treatment of the thyroid disorder,

Exclusion criteria

pregnancy, renal insufficiency, known osteoporosis, other disease that may affect bone metabolism, medication which affects bone metabolism, T-score below -3.5, thyroidea ophthalmopathy with indication for steroids,

Treatment and study plan

Primary outcomes

Thyroid Extreme CT

Time frame: one year

Bone cortical thickness in the radius measured by high-resolution peripheral quantitative CT, in newly diagnosed thyroid disorder, before and after treatment aimed to obtain euthyroidism

Sponsors and collaborators

Lead sponsor

Steen Bonnema

Other

Registry information

Important dates

Study start: 2012
Primary completion: 2016
Study completion: 2020
First posted: Dec 9, 2013
Registry last updated: Apr 13, 2020

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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