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NCT Number: NCT07196618

Bond Strength Evaluation

This study was evaluated the effect of dimethyl sulfoxide pretreatment on tensile bond strength and nanoleakage of resin composite bonded to aged dentin.

Active, Not Recruiting

This study is active but is not currently recruiting participants.

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Key information

Conditions

Bonding

Age range

50 year–75 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Al-Azhar university

Cairo, Egypt

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients included in the study will be required to present at least one of non caries cervical lesion with sclerotic dentin without pulpal involvement.
  • Age of patient: 50 - 75 years
  • Patients with non caries cervical lesion will be standardized by clinical performance (FDI world dental federation).

Exclusion criteria

  • Teeth with deep dentinal lesions with pulpal involvement, abscess, pain or swelling
  • Developmental disorders and adjacent soft tissue lesions
  • Patients with systemic illness will be excluded.

Treatment and study plan

Dimethyl Sulfoxide

Drug

dentin pretreated using dimethyl sulfoxide and follow up of patients at 2 weeks, 3 months and 6 months

Cholorhexidine

Drug

dentin pretreated using chlorhexidine and follow up of patients at 2 weeks, 3months and 6 months

Primary outcomes

  1. clinical assessment evaluation using the FDI world dental federation criteria

    Time frame: post operative 2 weeks

Secondary outcomes

  1. clinical assessment evaluation using the FDI world dental federation criteria

    Time frame: post operative 3 months and 6 months

Sponsors and collaborators

Lead sponsor

Al-Azhar University

Other

Registry information

Official study title

Effect of Dimethyl Sulfoxide Pretreatment on Tensile Bond Strength and Nanoleakage of Resin Composite Bonded to Aged Dentin

Acronym: DMSO

Important dates

Study start
2025
Primary completion
2026
Study completion
2026
First posted
Sep 29, 2025
Registry last updated
Dec 18, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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