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Completed

NCT Number: NCT03524521

Body Weight-Based Interval Training in Sedentary Overweight and Obese Adults

Body-weight based interval training (IT) performed 3 times per week will lead to reductions in abdominal adiposity and reduce overall body fat percentage in overweight and obese sedentary adults more effectively than moderate intensity continuous training (MICT). Body-weight interval training will improve exercise capacity (peak VO2) in overweight/obese adults.

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Key information

Age range

18 year–65 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Mayo Clinic in Rochester

Rochester, Minnesota, 55905, United States

About this study

Participants will be randomly assigned to one of the two home-based exercise groups.

The MICT group is the standard care group and will be instructed to walk for 30 minutes, 5 days per week at a moderate intensity. The goal is to accumulate 150 minutes of continuous aerobic exercise each week. Participants will be instructed on the use of the Rating of Perceived Exertion (RPE) scale during baseline testing and will be instructed to reach an RPE of 12-16. A heart rate monitor will be worn to monitor exercise intensity. Heart rate should reach ~70% of maximal heart rate.

The IT group will perform 5 body-weight exercises in three progressive phases. During the first 2 weeks the circuit will be completed twice, 30 second intervals, 90 seconds of rest. The exercises will be performed on 3 days of the week with at least one day of rest between exercise days (ideally Monday, Wednesday, Friday). The number of repetitions will increase to a maximum of 4 while the interval and rest periods increase to a maximum of 45 seconds each. The total time spent performing intervals by week 8 will be 15 minutes. A 2 minute warm up and 3 minute cool down will be performed, such as jumping jacks or simply walking. A heart rate monitor will be used to measure exercise intensity. Heart rate should reach approximately 90% of heart rate max during the intervals. Participants will be instructed on the use of the Rating of Perceived Exertion scale during baseline testing and will be instructed to reach an RPE of ≥17 during the high intensity intervals.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Adults 18-65 years of age
  • Willing and able to provide informed consent
  • Sedentary, overweight and obese adults (<90 minutes of moderate intensity exercise)
  • BMI 25≤35
  • Able to safely begin an exercise program
  • Have a smartphone, and willing and able to download and use the Fitbit app

Exclusion criteria

  • Unable to provide informed consent.
  • Known cardiovascular disease, or uncontrolled hypertension,
  • Diagnosed type 1 or 2 diabetes
  • Women who are pregnant or plan to become pregnant in the next 3-4 months
  • Orthopedic injury/limitation or any other contraindications to exercise.
  • Medications that cause weight gain (steroids, HIV-related medications, etc.), or glucose lowering medications

Treatment and study plan

Interval Training

Behavioral

Interval training is prescribed 3 days per week using 5 body weight exercises in a progressive fashion.

Standard of Care

Behavioral

Walking prescribed to meet current exercise guidelines; 150 minutes per week.

Primary outcomes

  1. Change in Body fat percent

    Time frame: 12 weeks

    DEXA derived body fat %

Secondary outcomes

  1. Change in Weight

    Time frame: 12 weeks

    Weight in kilograms

  2. Change in peak VO2

    Time frame: 12 weeks

    Peak VO2 in ml/kg/min

  3. Visceral adipose tissue area

    Time frame: 12 weeks

    cm^2

  4. Thigh adipose tissue area

    Time frame: 12 weeks

    cm^2

Sponsors and collaborators

Lead sponsor

Mayo Clinic

Other

Registry information

Official study title

The Effect of Interval Training Using Body Weight on Body Composition in Sedentary Overweight and Obese Adults

Important dates

Study start
2018
Primary completion
2021
Study completion
2021
First posted
May 14, 2018
Registry last updated
Jan 11, 2021

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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