Blood Collection From Individuals With Lung Disease for Genetic Studies

This is a research study where researchers are collecting blood to evaluate the genetic characteristics of individuals with chronic lung diseases, including asthma, chronic obstructive pulmonary disease (COPD), interstitial lung disease, cystic fibrosis, and lung cancer.

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Key information

Conditions

Asthma Bronchial Diseases COPD Chronic Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities Cystic Fibrosis Digestive System Diseases Disease Attributes Genetic Diseases, Inborn Hypersensitivity Hypersensitivity, Immediate Immune System Diseases Infant, Newborn, Diseases Interstitial Lung Disease Lung Cancer Lung Diseases Lung Diseases, Interstitial Lung Diseases, Obstructive Lung Neoplasms Neoplasms Neoplasms by Site Pancreatic Diseases Pathologic Processes Pathological Conditions, Signs and Symptoms Pulmonary Disease, Chronic Obstructive Respiratory Hypersensitivity Respiratory Tract Diseases Respiratory Tract Neoplasms Thoracic Neoplasms

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

New York Presbyterian Hospital -- Weill Cornell Medical College of Cornell University

New York, 10021, United States

About this study

The investigators hope to be able to identify an association between a genetic make-up in the blood samples and the risks of developing a particular lung disease, or severity of a lung disease. The findings of this study might be important to develop future preventative methods and potential treatments for the management of lung disease. The investigators aim to collect blood samples from 300 people with lung disease and 300 controls over 5 years.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Must provide informed consent
Males and females, age 18 years and older
Lung disease proven by at least one of the following:

symptoms consistent with pulmonary disease
chest X-rays consistent with lung disease
pulmonary function tests consistent with lung disease
lung biopsy consistent with lung disease
family history of lung disease
disease of organs with know associated with lung disease
individuals suspected of history of lung disease based on history and/or physical examination
normal controls (individuals without history of lung disease) to be sampled to provide a comparison to the lung disease cohort.

Exclusion criteria

Drug and/or alcohol abuse within the past six months
Females who are pregnant or nursing

Treatment and study plan

Primary outcomes

Establish a set of normal ranges for various parameters in healthy individual specimens and compare to specimens from individuals with lung disease to determine parameters resulting in disease susceptibility and severity.

Time frame: 5 years

Sponsors and collaborators

Lead sponsor

Weill Medical College of Cornell University

Other

Registry information

Official study title

Collection of Blood for Gene Expression/Genomic Studies in Individuals With Chronic Lung Disease

Important dates

Study start: 2005
Primary completion: 2015
Study completion: 2015
First posted: Aug 10, 2006
Registry last updated: Apr 29, 2016

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed