Skip to main content
OpenTrials
Completed

NCT Number: NCT02442895

Biomarkers of Ovarian Reserve and Correlation With IVF Treatments

Retrospective study to evaluate the correlation between AFC, FSHb, AMH and IVF outcomes of 347 cycles performed with three different protocols.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Pregnancy, Ovarian Female Urogenital Diseases and Pregnancy Complications Pregnancy Complications Pregnancy, Ectopic Urogenital Diseases

Sex eligibility

Female

Study type

Observational

Primary location

Azienda Ospedaliero Universitaria Consorziale Policlinico

Bari, 70124, Italy

About this study

347 IVF cycles (236 patients) analyzed for a retrospective study to evaluate the correlation between the biomarkers of ovarian reserve (antral follicles count, antimullerian hormone, basal follicle stimulating hormone) and number of oocytes and mature oocytes (MII) retrieved during the pick up. For the stimulation were used three different protocols: long luteal, antagonist with daily administration of gonadotropins and antagonist with depot administration of gonadotropins.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • women with primary or secondary infertility underwent ovarian stimulation for in vitro fertilization.

Exclusion criteria

  • women who underwent ovarian stimulation for cryopreservation in the presence of neoplastic disease.

Treatment and study plan

Primary outcomes

  1. number of total and mature (MII) oocytes

    Time frame: 10 months

    the number of total and mature (MII) oocytes retrieved during the pick up.

Secondary outcomes

  1. duration of stimulation

    Time frame: 10 months

    the number of days since the administration of rFSH o corifollitropina alfa until the administration of hCG

  2. ovarian sensitivity index or OSI

    Time frame: 10 months

    OSI was calculated dividing the total administered FSH dose by the number of retrieved oocytes

  3. pregnancy rate

    Time frame: 10 months

    the number of positive pregnancy tests with the evidence of an embyo with cardiac activity.

Sponsors and collaborators

Lead sponsor

U.O.S. Procreazione Medicalmente Assistita e Congelamento Gameti

Other

Registry information

Official study title

Predictors of Ovarian Response in Women Undergoing Ovarian Stimulation for IVF

Important dates

Study start
2014
Primary completion
2014
Study completion
2015
First posted
May 13, 2015
Registry last updated
May 13, 2015

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.