Biomarkers of Early Chronic Obstructive Pulmonary Disease (COPD) in Smokers - Longitudinal Study

This is a longitudinal observational study to identify and validate protein biomarkers for COPD (chronic obstructive pulmonary diseases) and cardiovascular disease in smokers and ex-smokers attending primary care. Special emphasize is to correlate biomarkers to different phases of COPD, to progression of the disease, and to treatment of the disease. Furthermore, linkage between COPD, cardiovascular disease, and lung cancer will be investigated by identifying protein biomarkers.

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Key information

Conditions

Chronic Obstructive Pulmonary Disease Behavior Cardiovascular Disease Cardiovascular Diseases Chronic Disease Disease Attributes Health Behavior Lung Cancer Lung Diseases Lung Diseases, Obstructive Lung Neoplasms Neoplasms Neoplasms by Site Pathologic Processes Pathological Conditions, Signs and Symptoms Pulmonary Disease, Chronic Obstructive Respiratory Tract Diseases Respiratory Tract Neoplasms Smoking Smoking Cessation Thoracic Neoplasms

Age range

35 year–80 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Örestadskliniken

Malmö, Sweden

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Diagnosed with COPD Gold stage 0-IV

Exclusion criteria

Patients with inflammatory diseases Patients with cancer Patients using immune system regulating drugs

Treatment and study plan

Primary outcomes

Advanced disease etiology requiring hospitalization.

Time frame: 2 years

Sponsors and collaborators

Lead sponsor

Lund University

Other

Collaborators

Örestadskliniken

Registry information

Official study title

Biomarkers of Early Chronic Obstructive Pulmonary Disease (COPD) and Cardiovascular Diseases in Smokers/Ex-Smokers Attending Primary Care - Longitudinal Study

Important dates

Study start: 2014
Primary completion: 2020
Study completion: 2020
First posted: Mar 3, 2014
Registry last updated: Aug 24, 2022

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed