An Open Prospective Longitudinal Pulmonary-cardiovascular Cohort Study

This is an observational study aiming to identify and validate biomarkers (including imaging and clinical descriptors) for chronic obstructive pulmonary disease (COPD), cardiovascular disease (CVD) and lung cancer.

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Key information

Conditions

Chronic Obstructive Pulmonary Disease Arterial Occlusive Diseases Arteriosclerosis Atherosclerosis Cardiovascular Diseases Chronic Disease Disease Attributes Lung Cancer Lung Diseases Lung Diseases, Obstructive Lung Neoplasms Neoplasms Neoplasms by Site Pathologic Processes Pathological Conditions, Signs and Symptoms Peripheral Arterial Disease Peripheral Vascular Diseases Pulmonary Disease, Chronic Obstructive Respiratory Tract Diseases Respiratory Tract Neoplasms Thoracic Neoplasms Vascular Diseases

Age range

45 year–75 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Skåne University Hospital

Lund, 221 85, Sweden

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

45-75 years

Sponsors and collaborators

Lead sponsor

Region Skane

Other

Registry information

Official study title

BIG3 - An Open Prospective Longitudinal Pulmonary-cardiovascular Cohort Study

Acronym: BIG3

Important dates

Study start: 2013
Primary completion: 2026
Study completion: 2026
First posted: Oct 26, 2011
Registry last updated: Aug 29, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

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