University of Copenhagen, Department of Biomedical Sciences
Copenhagen, 2200, Denmark
NCT Number: NCT03680768
The purpose of this cross-sectional study is to collect relevant molecular markers of aging and measures of physiological function. Together these biomarkers are used to develope a new Biological Age model, useful in health promotion interventions in the public health sector .
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Notify MeStudy design: 100 participants representing the healthy danish working adult population. This study seek to include both men and women equally distributed in the range of 18-65 of age.
Data collection: After recruitment, participants need to attend once to the laboratory, overnight fasted and without having exercised for the previous 24 hours.
All analyse are done in investigators lab (Xlab) at the department of Biomedical Sciences, Copenhagen University. When analyzes are done, the results are used in algorithm developement in cooperation with Technical university Denmark.
Healthy volunteers accepted: Yes
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
The protocol includes measurements of body composition, strength test, functional and fitness test as well as biochemical measurements from blood samples and AGEreader
Time frame: Day 1
A composite score of ones biological state (in years)
Time frame: Day 0
VO2max - maximal oxygen consumption (ml/min/kg)
Time frame: Day 0
Hand grip, isometric quadriceps and biceps strength (Nm)
Time frame: Day 0
Rise and sit from a chair as many times as possible during 1 minute (number og rises)
Time frame: Day 0
Waist to hip ratio is measured by dividing waist circumference with hip circumference in cm.
Time frame: Day 0
measured in kilograms
Time frame: Day 0
measured in cm
Time frame: Day 0
BMI (kg/m2) is calculated
Time frame: Day 0
muscle mass(g) is assessed by dual energy x-ray absorptiometry (DXA) and bioimpedance
Time frame: Day 0
fat mass(g) is assessed by DXA and bioimpedance
Time frame: Day 0
Fat%, is assessed by DXA and bioimpedance
Time frame: Day 0
HighDensityLipoprotein (mmol/L), LowDensityLipoprofile (mmol/L), TriGlycerides (mmol/L), FreeFattyAcids (mmol/L) and Glycerol (mmol/L) is measured in a blood sample.
Time frame: Day 0
Sex hormones: testosteron and estradiol (nmol/L) and InsulinGrowthFactor-1 (nmol/L) and Insulin (µU/ml) ais analysed from blood samples
Time frame: Day 0
C-reactive protein mg/L, soluble urokinase plasminogen activating receptor ng/ml, InterLeukin 6,8 and 10 (pg/mL), tumor necrosis factor (pg/mL), Leptin and Adiponectin (ng/ml) is analysed from blood samples
Time frame: Day 0
advanced glycation endproducts (AGE) measured in the skin
Time frame: Day 0
Profile picture taken to assess perceived age
Time frame: Day 0
forced vital capacity and forced expiratory volume at one second(L)
Time frame: Day 0
Systolic and Diastolic blood pressure (mmHg)
Time frame: Day 0
HbA1c and fasting glucose (mmol/L) measured from blood sample
Time frame: Day 0
Haematocrit and Haemoglobin (mmol/L) measured in a blood sample
Time frame: Day 0
Chemokines Eotaxin (CCL11) analysed from blood samples
Time frame: Day 0
Growth Differential Factor (GDF-11) analysed from blood samples
University of Copenhagen
Other
Development of a New Biological Age Technology Applicable in Public Health Promotion Interventions.
Acronym: BATE
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View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
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