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OpenTrials
Completed

NCT Number: NCT05888779

Beverages for Thought: Exploring the Relationship Between Blood Glucose and Cognition

The objective of this study is to conduct novel research on the relationship between blood sugar and cognition.

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Key information

Age range

18 year–65 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

USDA Grand Forks Human Nutrition Research Center

Grand Forks, North Dakota, 58203, United States

About this study

This study is an acute parallel study design with one intervention visit needed per participant. There are 2 groups and 80 participants will be randomized into each group. Following the consent process, participants in each group will be seated individually in quiet rooms, with written instructions, several magazines, and a mini-fridge with beverages containing 110-120 kcals/8 fl oz. Participants will be provided instructions for the study, stating, "The study we are conducting explores the relationship between blood glucose and cognitive abilities. After consuming food or drink, your body regulates your blood glucose. Physical exertion can also affect blood glucose. Therefore, we ask that you relax in this space for 10-15 minutes. You can read the provided magazines during this time. Drinking a beverage will bring your body's blood glucose into the right phase for our questionnaires. In the fridge are some beverages, and we ask that you drink something."

After 10-15 minutes, participants will be given a cognitive test (a questionnaire on paper) and asked to complete as much of it as they can within 5 minutes. Then, moving to a separate area, weight and height measurements will be taken.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • No food allergies or food intolerances
  • Healthy (no chronic disease) as determined by online questionnaire
  • Non-pregnant and non-lactating
  • Not currently dieting or planning to follow a special diet
  • Minimal restricted eating practices

Exclusion criteria

  • Pregnant or lactating
  • Currently dieting or planning to follow a special diet

Treatment and study plan

Beverage One (Milk)

Other

Participant will consume beverage one (milk) and complete novel cognitive assessment questionnaire on paper.

Beverage Two (Juice)

Other

Participant will consume beverage two (fruit drink) and complete novel cognitive assessment questionnaire on paper.

Primary outcomes

  1. Written cognitive task results from novel cognitive assessment questionnaire.

    Time frame: 10 minutes post beverage ingestion

    Results of cognitive task after consuming a study beverage (milk or fruit-flavored drink). More questions answered correctly results in a higher score. The assessment has a total of 10 questions, and participants will be asked to complete as much of this assessment as they can within a 5 minute timeframe.

Sponsors and collaborators

Lead sponsor

USDA Grand Forks Human Nutrition Research Center

Fed

Registry information

Important dates

Study start
2023
Primary completion
2025
Study completion
2025
First posted
Jun 5, 2023
Registry last updated
Apr 23, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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