Beta Glucan 500 and Biological Age and Immune Age

The primary purpose of this study is to evaluate the effects of BWH Labs - Beta Glucan 500 on biomarkers of biological and immune age among healthy adults.

A single-arm, open-label prospective study will be conducted evaluating the impact of 12 weeks of supplementation with two capsules daily of Beta Glucan 500 on a variety of validated markers of biological and immune age on the comprehensive TruAge panel (TruDiagnostics, Lexington, KY).

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Aging

Age range

40 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 2

Primary location

OvationLab

Richmond, Virginia, 23220, United States

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Adult females or males age ≥ 40 years
Ability to read and speak English
Previous completion of a TruDiagnostic TruAge test within the past three months to enable comparison of previous biomarkers to the same biomarkers after intervention
DunedinPACE estimate of aging >0.9

Exclusion criteria

Current diagnosis and treatment for an autoimmune condition
Current use of beta-glucan or mushroom dietary supplement
Known allergies to beta glucan, yeast, or mushrooms
Currently pregnant or lactating women or women planning to become pregnant in the next 12 weeks
Current diagnosis of a chronic health condition (e.g., cancer, heart failure, history of pancreatitis, type I or II diabetics on insulin) deemed clinically contraindicated for the study protocol
Participants unable to provide consent

Treatment and study plan

Beta Glucan

Dietary Supplement

12 weeks of supplementation with two capsules daily of BWH Labs Beta Glucan 500

Primary outcomes

Epigenetic Testing

Time frame: Change from baseline to 12 weeks

Sponsors and collaborators

Lead sponsor

OvationLab

Network

Registry information

Official study title

Prospective Human Study Evaluating the Effects of Beta Glucan 500 on Markers of Biological Age and Immune Age: An Open-label Pilot Study

Important dates

Study start: 2025
Primary completion: 2025
Study completion: 2025
First posted: Aug 5, 2025
Registry last updated: Feb 19, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed