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Completed

NCT Number: NCT07340996

Beta Caryophyllene & Apnea Performance

The purpose of this study is to investigate whether β-caryophyllene supplementation can enhance the static apnea capacity of freedivers.

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Key information

Age range

20 year–40 year

Sex eligibility

Male

Study type

Interventional

Phase

Not applicable

Primary location

National Taiwan University of Sport

Taichung, Taiwan

About this study

Using a randomized crossover design with double-blind methodology, participants were assigned to either the β-caryophyllene trial (BCP) trial or the placebo (PLA) trial, which without β-caryophyllene. Participants consumed either 200 mg of β-caryophyllene capsules (BCP trial) or placebo capsules (PLA trial) based on pre-test results. After a 30-minute rest period and warm-up, a single maximal voluntary static breath-hold test was conducted. Breath-hold duration and physiological and salivary biochemical indicators before and after the breath-hold test were observed.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • With over 3 years of freediving experience

Exclusion criteria

  • Without over 3 years of freediving experience

Treatment and study plan

interventions

Dietary Supplement

supplementation of β-caryophyllene

Placebo

Dietary Supplement

Participants consumed placebo capsules (PLA trial)

Primary outcomes

  1. Breath-hold duration

    Time frame: 30 minutes after intervention

    Measure the duration of static breath-holding

Sponsors and collaborators

Lead sponsor

Chih-Hui Chiu

Other

Collaborators

  • National Science and Technology Council, Taiwan

Registry information

Official study title

Effects of Beta Caryophyllene Supplementation on Autonomic Regulation and Apnea Performance in Elite Divers - a Randomized Crossover Trial

Important dates

Study start
2026
Primary completion
2026
Study completion
2026
First posted
Jan 14, 2026
Registry last updated
Apr 29, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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