UCSD Eating Disorders Treatment and Research Program
La Jolla, California, 92121, United States
Location status: Recruiting
Location contact
Christina E Wierenga, PhD
PRINCIPAL_INVESTIGATOR
Katherine Gandee, BS
CONTACT
Sophie R Abber, MS
CONTACT
NCT Number: NCT06566612
The purpose of this study is to investigate areas of the brain responsible for avoidance learning in adults with eating disorders using brain imaging techniques, computer tasks, and self-report questionnaires and interviews. The investigators will study changes in brain activity using a procedure called functional magnetic resonance imaging (fMRI). This study will include 78 women with an eating disorder (26 with anorexia nervosa [AN], 26 with bulimia nervosa [BN]) and 26 healthy controls (HC) aged 18-39.
Aim 1: Evaluate behavioral differences in active and passive avoidance learning in eating disorders and associations with symptoms.
Aim 2: Evaluate whether corticostriatal and limbic-prefrontal fMRI BOLD response associated with avoidance learning differs in eating disorders relative to healthy controls and relates to symptoms.
Aim 3: Evaluate whether functional connectivity of avoidance learning neural circuity differs in eating disorders relative to healthy controls.
Interested in participating?
Request Info18 year–39 year
Female
Observational
La Jolla, California, 92121, United States
Location status: Recruiting
Christina E Wierenga, PhD
PRINCIPAL_INVESTIGATOR
Katherine Gandee, BS
CONTACT
Sophie R Abber, MS
CONTACT
Healthy volunteers accepted: Yes
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Eating Disorder Group:
Healthy Controls:
Exclusion criteria
Additional Exclusion Criteria for ED Group:
Additional Exclusion Criteria for Healthy Control Group:
Time frame: 25 minutes
Behavioral responses during a card game gambling task
Time frame: 25 minutes
fMRI brain activity associated with the card game gambling task
Time frame: 10 minutes
Whole-brain functional connectivity associated with the card game gambling task
Contact information is provided by the study sponsor or research team.
University of California, San Diego
Other
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View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
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