AVF Stenosis by Electronic Stethoscope

The prevalence rate of hemodialysis in Taiwan is the highest in the world, and the number of new cases of hemodialysis and the death rate are gradually increasing every year. Long-term hemodialysis patients must receive dialysis through the arteriovenous fistula. If the arteriovenous fistula is narrowed, the dialysis effect will be poor or the dialysis will not be possible due to blockage, resulting in complications and mortality. The detection of the arteriovenous fistula must rely on the assistance of professionals.

* Is it easier for clinicians to detect arteriovenous fistula stenosis by an electronic stethoscope?

This study uses an electronic stethoscope to take the hemodialysis center of Douliu District, Yunlin Branch of National Taiwan University Hospital as the experimental site. Select 30 patients who need long-term dialysis, adults (20-99 years old) who have been on dialysis for more than 3 months and have arteriovenous fistula. The experiment period lasted for 3 months, and each person received 2-3 voices per week, about 1080 voices. The main purpose is to use the electronic stethoscope and the experience of traditional professionals, hoping to detect and predict the stenosis in advance. The important key factors of vascular access stenosis in hemodialysis patients were found through regression analysis of the Albumin value and clinical data obtained from routine treatment of patients of a fixed blood test in monthly hemodialysis center.

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Key information

Conditions

End Stage Renal Disease (ESRD) Arteriovenous Fistula Arteriovenous Malformations Cardiovascular Abnormalities Cardiovascular Diseases Chronic Disease Congenital Abnormalities Congenital, Hereditary, and Neonatal Diseases and Abnormalities Disease Attributes Female Urogenital Diseases Female Urogenital Diseases and Pregnancy Complications Fistula Kidney Diseases Kidney Failure, Chronic Male Urogenital Diseases Pathologic Processes Pathological Conditions, Anatomical Pathological Conditions, Signs and Symptoms Renal Insufficiency Renal Insufficiency, Chronic Urogenital Diseases Urologic Diseases Vascular Diseases Vascular Fistula Vascular Malformations

Age range

20 year–99 year

Sex eligibility

All sexes

Study type

Observational

Primary location

National Taiwan University Hospital Yunlin Branch

Douliu, Taiwan, 640

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Age 20-99 years - Chronic hemodialysis ≥3 months - Functional arteriovenous fistula (AVF) - Ability to provide informed consent

Exclusion criteria

Arteriovenous graft (AVG) - Central venous catheter (Permcath) - Vulnerable populations unable to consent

Treatment and study plan

Detection and Prediction of the stenosis of arteriovenous fistula in hemodialysis patients by an electronic stethoscope

Device

The detection of the arteriovenous fistula must rely on the assistance of professionals by palpation or a conventional stethoscope. This study will investigate the detection and prediction of arteriovenous fistula stenosis in hemodialysis patients by an electronic stethoscope.

Primary outcomes

AVF stenosis

Time frame: From enrollment to the end of study at 3 months

Clinical stenosis: Diagnosed by attending nephrologist based on physical examination abnormalities (high-pitched bruit, pulsatile flow, diminished thrill) - Confirmed by Doppler ultrasound showing >50% diameter reduction - Intervention: Percutaneous transluminal angioplasty (PTA)

Secondary outcomes

Abnormal AVF sound threshold

Time frame: From enrollment to the end of study at 3 months

Defined using statistical analysis of post-PTA normal sounds

Sponsors and collaborators

Lead sponsor

National Taiwan University Hospital

Other

Registry information

Official study title

Detection and Prediction of the Stenosis of Arteriovenous Fistula in Hemodialysis Patients by an Electronic Stethoscope

Important dates

Study start: 2023
Primary completion: 2023
Study completion: 2023
First posted: Feb 27, 2026
Registry last updated: Feb 27, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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