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OpenTrials
Completed

NCT Number: NCT02397681

Autonomic Responses During the Valsalva Maneuver and Deep Breathing Test Depend on the Experimental Setup

The purpose of this study is to determine the effects of procedural differences during the Valsalva maneuver and deep breathing test in autonomic nervous system testing.

Completed

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Key information

Conditions

Autonomic Nervous System Diseases Nervous System Diseases

Age range

18 year and older

Sex eligibility

Male

Study type

Interventional

Phase

Not applicable

Primary location

Danish Pain Research Center, Aarhus University Hospital

Aarhus, 8000, Denmark

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • male
  • ≥ 18 year
  • normal ECG-12

Exclusion criteria

  • any known disease
  • smoking
  • any intake of regular medicine

Treatment and study plan

Autonomic Function Testing

Other

Autonomic nervous system index assessed with Task Force Monitor (CNSystems Medizintechnik AG, Graz, Austria)

Primary outcomes

  1. Blood pressure changes to cardiovascular adrenergic activation

    Time frame: 3 hours

  2. Heart rate changes to parasympathetic activation

    Time frame: 3 hours

Secondary outcomes

  1. Expiratory pressure during the Valsalva maneuver

    Time frame: 3 hours

  2. Expiratory duration during the Valsalva maneuver

    Time frame: 3 hours

  3. Air volume exchanged per respiratory cycle during deep respiration

    Time frame: 3 hours

Sponsors and collaborators

Lead sponsor

Danish Pain Research Center

Other

Collaborators

  • Aalborg University
  • Mayo Clinic

Registry information

Important dates

Study start
2015
Primary completion
2015
Study completion
2015
First posted
Mar 25, 2015
Registry last updated
Jan 31, 2018

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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