Autologous Fat Grafting With PRP (Platelet Rich Plasma) to Anophthalmic Sockets

After people lose an eye, for whatever reason, they often experience fat atrophy of the tissues in the orbit. This leads to a sunken appearance that is often not correctable by a cosmetic shell prosthesis. Current techniques to correct this deformity are inadequate/ invasive. Injection of various gels (Restylane, Radiesse) are temporary had have their own disadvantages. This study seeks to demonstrate an improvement in the retention of injected autologous fat by mixing in autologous PRP (platelet rich plasma).

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Key information

Conditions

Orbital Atrophy Anophthalmos Congenital Abnormalities Congenital, Hereditary, and Neonatal Diseases and Abnormalities Eye Abnormalities Eye Diseases

Age range

21 year–70 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

New York Eye and Ear Infirmary

New York, 10003, United States

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

anophthalmos, orbital atrophy -

Exclusion criteria

poor anesthesia risk, people outside a 100 mile radius of New York City

Treatment and study plan

autologous fat grafting with PRP to anophthalmic orbits

Procedure

Primary outcomes

Improved retention of autologous fat injected into anophthalmic sockets

Time frame: 1-5 yrs

Non contrast MRIs of the orbits are obtained before, immediately after, and one year after injection of autologous fat mixed with autologous PRP (platelet rich plasma)

Sponsors and collaborators

Lead sponsor

Fox, Donald Munro, M.D., P.C.

Indiv

Registry information

Official study title

Autologous Fat Grafting to Anophthalmic Sockets With PRP (Platelet Rich Plasma) Using a Closed Cannula Technique

Important dates

Study start: 2011
Primary completion: 2017
Study completion: 2017
First posted: Oct 23, 2012
Registry last updated: Aug 20, 2018

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed