Autogenous Tooth Bone Graft for Alveolar Socket Preservation

The purpose of this clinical experiment is to assess how well autogenous tooth bone grafting preserves the alveolar socket after surgical tooth extraction. Before being inserted into the socket, the graft is made from the patient's own extracted tooth and ground into a particle. Twenty Yemeni patients who needed their teeth extracted are included in the trial, and they will be followed up with clinical and radiographic procedures using cone-beam computed tomography (CBCT) for six months. The primary objective is to ascertain whether the autogenous dental bone graft can preserve the height, width, and density of alveolar bone, offering a secure, affordable, and biocompatible substitute for traditional grafting materials.

Active, Not Recruiting

This study is active but is not currently recruiting participants.

Key information

Conditions

Alveolar Bone Grafting Bone Regeneration Following Wisdom Teeth Extraction Tooth Extraction Site Healing

Age range

18 year–40 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Sana'a University faculty of Dentisrty

Sanaa, Sanaa Governorate, Yemen

About this study

This interventional clinical study investigates the role of autogenous tooth bone graft in alveolar socket preservation after surgical tooth extraction. The extracted tooth is cleaned, dried, processed into particulate graft material manually using bone crusher, and disinfect and treated using (NaOH) and (Na CL). The graft particles are immediately placed into the fresh extraction socket and sutured. Twenty Yemeni patients requiring impacted lower third molar and upper canine teeth surgical extractions will be included. The healing process will be evaluated both clinically and radiographically over a 6-month period. Cone-beam computed tomography (CBCT) scans will be used to assess bone density and alveolar ridge dimensions before extraction and at six months' post-intervention. The study aims to determine whether autogenous tooth bone grafts can effectively reduce post-extraction alveolar bone resorption and maintain ridge dimensions, supporting their potential use as an autologous, biocompatible, and economically feasible graft material for clinical socket preservation.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

- Absence of systemic diseases.
Very good to accepted oral hygiene.
Patients with impacted teeth requiring extraction.
Patients between the ages of 16 and 50.
No history of smoking.
No history of any other drug use.
Patients who were cooperative, motivated, to attend the follow-up and maintenance visits.

Exclusion criteria

Systemic conditions or pharmacological therapies that could be an absolute contraindication for the intervention (such as un controlled diabetics, immunocompromised states, or treatment with oral or parenteral bisphosphonates).
Poor oral hygiene.
Acute exacerbation of chronic infection like pain or swelling.
Pregnant women, children, elderly (>60 years), physically and mentally challenged, terminally and seriously ill.
Hight Smoking tendency.
Patients who refused to participate in the trial.
Uncooperative Patients who won't be able to maintain the follow up visits

Treatment and study plan

"Autogenous Tooth Bone Graft"

Biological

"The intervention involves the use of the patient's own extracted tooth to create a bone graft for alveolar socket preservation following surgical tooth extraction. The patient's tooth is carefully processed to remove caries, periodontal ligaments, pulp, and any restorative materials, leaving behind a complete tooth structure (enamel, dentin, and cementum). This tooth is then crushed, disinfected, and treated before being placed into the empty socket. This graft helps maintain the structure of the alveolar bone by promoting natural bone regeneration and preventing resorption. The bone graft will be monitored for its efficacy in preserving alveolar bone height, width, and density, assessed using Cone Beam Computed Tomography (CBCT)."

Primary outcomes

"Alveolar Bone Height, Width, and Density Preservation with Autogenous Tooth Bone Graft"

Time frame: "Before extraction and 6 months post-intervention"

This study aims to evaluate the effectiveness of autogenous tooth bone grafts in preserving alveolar bone following tooth extraction. The study will assess changes in alveolar bone height, width, and density using Cone Beam Computed Tomography (CBCT) at two time points: before extraction (baseline) and 6 months post-grafting.

The outcome measures are:

Alveolar Bone Height: Measured in millimeters using CBCT at baseline and 6 months.

Alveolar Bone Width: Measured in millimeters using CBCT at baseline and 6 months.

Alveolar Bone Density: Measured in Hounsfield units using CBCT at both time points.

The intervention involves using the patient's own extracted tooth to create a bone graft placed into the socket, promoting healing and bone regeneration. This study will determine the effectiveness of autogenous tooth bone grafts in preventing bone resorption and preserving alveolar socket structure.

Sponsors and collaborators

Lead sponsor

Haifaa Mohammed Al-hussini

Other

Registry information

Official study title

"Autogenous Tooth Bone Graft for Alveolar Socket Preservation: A CBCT-Based Clinical Trial With 6-Month Follow-Up"

Acronym: ATBG

Important dates

Study start: 2024
Primary completion: 2025
Study completion: 2026
First posted: Dec 5, 2025
Registry last updated: Dec 5, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Recruiting