Skip to main content
OpenTrials
Completed

NCT Number: NCT03805165

Associations of Nighttime Light Exposure During Pregnancy With Neonatal Jaundice：a Multi-centre Prospective Study in China

Make a neonatal jaundiced nomogram on Chinese jaundice data by joinning the major neonate centers all around China.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Jaundice, Neonatal Congenital, Hereditary, and Neonatal Diseases and Abnormalities Hyperbilirubinemia Hyperbilirubinemia, Neonatal Infant, Newborn, Diseases Pathologic Processes Pathological Conditions, Signs and Symptoms

Age range

1 day–7 day

Sex eligibility

All sexes

Study type

Observational

Primary location

Jie Yang

Guangzhou, Guangdong, 511442, China

About this study

This was a multi-centre prospective study. All infants included were born in 8 hospitals in the southern, eastern, northern, western and central regions of mainland China in 2019. A total of 20839 transcutaneous bilirubin(TCB) measurements were performed with 2977 neonates at designated time points. The mean NTL exposure during pregnancy was respectively calculated based on each participant's residential address over the study course. The primary outcome was whether the neonate was diagnosed with hyperbilirubinemia within the first seven days of life. The effect of maternal nocturnal light exposure on neonate jaundice analyzed with lasso regression and random forest machine learning methods.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

gestational age more than 35 weeks(≥35) -

Exclusion criteria

all kinds of congenital diseases, infants with pathologic jaundice

-

Treatment and study plan

Primary outcomes

  1. Hour-specific Transcutaneous Bilirubin Level

    Time frame: 1 year

    make neonatal jaundiced nomogram base on the hour-specific transcutaneous bilirubin data

  2. whether the neonate was diagnosed with hyperbilirubinemia within the first seven days of life

    Time frame: 2019

    whether the neonate was diagnosed with hyperbilirubinemia within the first seven days of life

Sponsors and collaborators

Lead sponsor

Guangdong Women and Children Hospital

Other

Registry information

Acronym: jaundice

Important dates

Study start
2019
Primary completion
2019
Study completion
2019
First posted
Jan 15, 2019
Registry last updated
Dec 3, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.