Assessment of TFT by OCT in Healthy Subjects and Subjects With DES

Inclusion criteria

Inclusion criteria

for healthy volunteers

• Men and women aged over 18 years
• Normal findings in the medical history unless the investigator considers an abnormality to be clinically irrelevant
• Normal ophthalmic findings, ametropia < 6 Dpt.

Inclusion criteria

for patients with DES:

• Men and women aged over 18 years
• DES patients will be included based on three questions:

• (1) "Have you ever been diagnosed (by a clinician) as having dry eye syndrome?"
• (2) "Do you currently use artificial tear eyedrops or gel?"
• (3) "For the past three months or longer, have you had dry eyes? (This is described as a foreign body sensation with itching and burning, sandy feeling, not related to allergy)."
• Normal ophthalmic findings except dry eye syndrome

Exclusion criteria

• Participation in a clinical trial in the 3 weeks preceding the study
• Symptoms of a clinically relevant illness in the 3 weeks before the first study day
• Wearing of contact lenses
• Intake of dietary supplements in the 3 months preceding the study
• History of glaucoma
• Treatment with corticosteroids in the 4 weeks preceding the study to topical treatment with any ophthalmic drug in the 4 weeks preceding the study (topical lubricants for patients with DES are allowed)
• Ocular infection or clinically significant inflammation
• Ocular surgery in the 3 months preceding the study
• Sjögren's syndrome
• Stevens-Johnson syndrome
• Pregnancy, planned pregnancy or lactating