Advanced Fetal Cair Unit - Assiut University
Asyut, Egypt
NCT Number: NCT03146507
The fetal heart plays a central role in the adaptive mechanisms for hypoxemia and placental insufficiency. Longitudinal data on the hemodynamic sequence of the natural history of fetal growth restriction show that the umbilical artery and middle cerebral artery are the first variables to become abnormal . These arterial Doppler abnormalities are followed by abnormalities in the right cardiac diastolic indices, followed by the right cardiac systolic indices, and finally by both left diastolic and systolic cardiac indices .
Preserving the left systolic function as the last variable to become abnormal ensures an adequate left ventricular output , which supplies the cerebral and coronary circulations.This defence is contingent on the fetal cardiovascular system, which in late gestation adopts strategies to decrease oxygen consumption and redistribute the cardiac output away from peripheral vascular beds and towards essential circulations, such as those perfusing the brain.
Adding cardiac Doppler may improve management of the IUGR fetus(intrauterine growth retardation), Doppler ultrasound is valuable in defining the degree of cardiovascular compromise in at-risk pregnancies. The severity of fetal blood flow redistribution shows the degree of fetal adaptation and provides information on how long the pregnancy can be continued safely.
The aime of the study is assessment of cardiac output redistribution in fetal hypoxia by estimating relative right to left side cardiac output wich reflect cardiac sparing in (IUGR).
Looking for future studies?
Notify Me20 year–35 year
Female
Interventional
Not applicable
Asyut, Egypt
Healthy volunteers accepted: Yes
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
ultrasound assessment of gestational age, amniotic fluid index, and fetal weight
Umbilical artery and Middle cerebral artery Doppler blood flow assesment
The cardiac output (ratio between right side cardiac outputs to left side cardiac output) was calculated
Time frame: 1 month
Time frame: 1 month
Time frame: 1 month
Time frame: 1 month
Time frame: 15 minutes
Time frame: 7 weeks
Time frame: 7 weeks
Assiut University
Other
Doppler Echocardiography Assessment of Cardiac Sparing Effect in Fetal Hypoxia
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
Published trials that share one or more normalized conditions with this study.
NCT04876846
Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Female Urogenital Diseases and Pregnancy Complications
Walnut Creek, California, United States
View Trial DetailsNCT06405984
Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Female Urogenital Diseases and Pregnancy Complications
Norfolk, Virginia, United States
View Trial DetailsNCT02741284
Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Electronic Fetal Monitoring
St Louis, Missouri, United States
View Trial DetailsNCT02377817
Behavior, Congenital, Hereditary, and Neonatal Diseases and Abnormalities
Halifax, Nova Scotia, Canada
View Trial Details