Assessing Ocular Surface Changes After Changing Glaucoma Medications

Hypothesis: Changing to Travatan Z therapy increases the tear film break up time of subjects on Xalatan therapy presenting with ocular surface disease.

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Key information

Conditions

Glaucoma Eye Diseases Monotherapy With Xalatan From 1 to 18 Months Ocular Hypertension Ocular Surface Disease

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Rocky Mountain Lions Eye Institute

Aurora, Colorado, 80045-0510, United States

About this study

Patients who have been taking Xalatan monotherapy to treat their glaucoma and presenting with ocular surface disease will be advised to switch their medication to Travatan Z. Test results will be recorded at the day that the medication was changed and at follow-up to determine if there is a measurable change in tear film break up, corneal staining and in the Ocular Surface Disease Index.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

on Xalatan monotherapy from 1 to 18 months
18 years of age or older
has been diagnosed with ocular surface disease

Exclusion criteria

special populations such as children, pregnant females, prisoners, etc.

Treatment and study plan

Primary outcomes

Change in Signs and Symptoms of Ocular Surface Disease

Time frame: 6 months

Sponsors and collaborators

Lead sponsor

University of Colorado, Denver

Other

Registry information

Official study title

Assessing Changes at the Ocular Surface Following the Switch From Xalatan to Travatan Z.

Important dates

Study start: 2007
Primary completion: 2011
Study completion: 2011
First posted: Nov 6, 2007
Registry last updated: Jan 27, 2017

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed