Skip to main content
OpenTrials
Completed

NCT Number: NCT00273442

Assessing Cosopt Switch Patients

To assess the safety and efficacy of a cohort of patients switched to the dorzolamide/timolol maleate fixed combination because they are insufficiently controlled on latanoprost monotherapy.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Ocular Hypertension Exfoliation Syndrome Eye Diseases Glaucoma Glaucoma, Open-Angle Glaucoma, Pigmentary Iris Diseases Open-angle Glaucoma Uveal Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 4

Primary location

Little Rock Eye Clinic, Little Rock, Arkansas, United States

Loading trial locations.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • adults with clinical diagnosis of POAG, pigment-dispersion or exfoliation glaucoma or ocular hypertension
  • the IOP on latanoprost must be 31 mm Hg or less in both eyes, and 21 to 31 mm Hg inclusive in at least one eye at 08:00 AM
  • visual acuity should be 20/200 or better in each eye

Exclusion criteria

  • contraindications to study drugs
  • anticipated change in systemic hypotensive therapy during the trial
  • use of any corticosteroids by any route in the three months immediately prior to Visit 2

Treatment and study plan

timolol maleate

Drug

dorzolamide/timolol maleate fixed combination

Drug

Sponsors and collaborators

Lead sponsor

Pharmaceutical Research Network

Other

Registry information

Important dates

Study start
2005
Study completion
2007
First posted
Jan 9, 2006
Registry last updated
Nov 19, 2008

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.