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Completed

NCT Number: NCT00405613

Aspirin Use and Postoperative Bleeding From Dental Extractions in a Healthy Population

The purpose of this study is to determine if aspirin is associated with bleeding complications following a single tooth extraction

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Key information

Conditions

Bleeding Complication Hemorrhage Pathologic Processes Pathological Conditions, Signs and Symptoms

Age range

18 year–80 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 2

Primary location

Carolinas Medical Center

Charlotte, North Carolina, 28232, United States

About this study

Aspirin is a common chronically administered preventive treatment for cardiovascular disease, but is often discontinued prior to invasive dental procedures because of concern of bleeding complications. As the goal of aspirin is often to prevent MI and stroke, the risk of these CVD outcomes with discontinuation of aspirin must be weighed against the perceived adverse event of bleeding during or following an invasive dental procedure with continuation of aspirin. The current study is a randomized controlled trial evaluating bleeding complications of aspirin vs. placebo in healthy patients schedule for a single tooth extraction.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Healthy
  • Require a simple tooth extraction

Exclusion criteria

  • Use of previous aspirin or NSAID

Treatment and study plan

Aspirin

Drug

Primary outcomes

  1. Oral bleeding time

Secondary outcomes

  1. Report of bleeding at phone follow-up at 3-7 (first follow-up) and 40-55 hours (second follow-up)

Sponsors and collaborators

Lead sponsor

Wake Forest University Health Sciences

Other

Registry information

Important dates

Study start
2003
Study completion
2005
First posted
Nov 30, 2006
Registry last updated
Apr 25, 2022

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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