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NCT Number: NCT07087119

Artificial Intelligence Powered Mental Health Support Tool For Physicians In Training

The purpose of this pilot study is to evaluate the acceptability of an artificial intelligence powered mental health support tool for mental health wellness amongst physicians in training.

The primary research procedures are:

The primary research procedure will be the utilization of artificial intelligence powered mental health support session through a web browser for physicians in training to address symptoms related to depression and anxiety. A pre and post intervention survey, evaluating depression symptoms with the standardized PHQ-9 questionnaire and anxiety symptoms with the standardized GAD-7 questionnaire will be conducted to assess changes in mental health wellness.

The study will enroll physicians in training, including Internal Medicine residents and Gastroenterology fellows.

The study includes at least 4 sessions. The total study duration for each subject is 3 months.

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Cedars Sinai Medical Center

Los Angeles, California, 90048, United States

About this study

This is a prospective pilot study with internal medicine residents and gastroenterology fellows to evaluate the role of AI mental health support tool as a wellness resource.

Participants will be invited via e-mail to participate in the study. The invitation e-mail will describe the study and ask that those who meet exclusion criteria do not participate in this pilot study. The e-mail will also include a file with information of the study for participants to review including how study members are blinded and the de-coding process required for participants to be contacted by a study member should they score >15 on PHQ-9 and or >10 on GAD-7. Those who choose to participate will be asked to email a study member who will send the participants a REDCap link to the consent, survey and a code to be used in the survey.

Participants will be asked to complete a set of questionnaires to evaluate their mental health and factors that contribute to mental health as well as four AI powered mental health support sessions over a four-week period. This will conclude the active phase of their participations. Participants will then be sent a questionnaire at 3 months from study initiation to complete a questionnaire evaluating their mental health and if they would be interested in additional AI powered mental health support sessions.

The questionnaires will be administered before the AI sessions and at the end of the study period to evaluate for changes in mental health scores. The questionnaires will include the validated PHQ-9 for a standardized depression score and the GAD-7 for a standardized anxiety score to evaluate symptoms related to depression and anxiety. In addition, a set of questions will focus on demographics, work and home environment to evaluate factors that may contribute to mental health prior to the AI sessions and a set of questions related to the AI sessions at the end of the study period. The questionnaire will be administered via REDCap.

The AI powered sessions will be administered via a web browser such as a computer, laptop, tablets or cellphone. Participants can complete the session in the privacy of their home or in a private location at work such as a call-room. Participants will be asked to complete one 20-minute session per week during the 4-week study period for a total of four sessions.

The AI program used will be the XAIA software program. Participants will be sent an email with the link to use the XAIA software. This includes a tutorial on how to use XAIA.

The duration of the study session is 4 weeks and total duration of the study is three months.

The study will be conducted at one site only, Cedars-Sinai or participants may conduct the sessions at the privacy of their own home.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Individuals 18 years old or older are included.
  • Training physicians in Internal Medicine residency and Gastroenterology fellowship at Cedars Sinai.
  • Study is limited to Cedars-Sinai employees who are known to speak English.

Exclusion criteria

  • Active treatment of severe and uncontrolled anxiety or depression with a health care professional
  • Unwilling and or unable to participate
  • Non-English speakers.

Treatment and study plan

utilization of artificial intelligence powered mental health support session through a web browser

Behavioral

utilization of artificial intelligence powered mental health support session with the software XAIA through a web browser for physicians in training to address symptoms related to depression and anxiety.

Primary outcomes

  1. Feasibility of using Artificial Intelligence sessions as a wellness resource

    Time frame: 3 months

    Investigators will evaluate the percentage of participants who find the Artificial Intelligence Sessions to be easily accessible and helpful.

Secondary outcomes

  1. Prevalence of depression and anxiety in training physicians

    Time frame: 3 months

    Determine the % of participants who have symptoms of depression and anxiety in training

  2. Determine work-related and home-related factors that impact trainee mental health

    Time frame: 3 months

    Evaluate percentage of participants who have work-related and home-related factors impacting mental health

Study contacts

Contact information is provided by the study sponsor or research team.

Barbara Hollander, MD

CONTACT

[email protected]

Kavya Reddy, MD

CONTACT

[email protected]

(310) 423-2811

Sponsors and collaborators

Lead sponsor

Cedars-Sinai Medical Center

Other

Registry information

Official study title

A Pilot Study: Exploring The Role Of an Artificial Intelligence Powered Mental Health Support Tool For Mental Health Wellness For Physicians In Training

Important dates

Study start
2025
Primary completion
2026
Study completion
2026
First posted
Jul 25, 2025
Registry last updated
Jul 25, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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