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Completed

NCT Number: NCT02932124

Application of Mechanical Cardiopulmonary Resuscitation Devices and Their Value in Out-of-hospital Cardiac Arrest: A Retrospective Analysis of the German Resuscitation Registry

The aim of this study was to analyse a large CPR database, the German Resuscitation Registry, to evaluate potential benefits of mechanical CPR devices over manual CPR in adult cardiac arrest victims. The primary endpoint considered is ROSC.

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

About this study

In a retrospective analysis of the German Resuscitation Registry between 2007-2014, investigators examined the outcome after using mechanical CPR on return of spontaneous circulation (ROSC) in adults with out-of-hospital cardiac arrest (OHCA). Investigators compared mechanical CPR (Intervention group) to manual CPR (control group). According to preclinical risk factors, investigators calculated the predicted ROSC-after-cardiac-arrest (RACA) score for each group, and compared it to the rate of ROSC observed. Using multivariate analysis, investigators adjusted the influence of the devices' application on ROSC for epidemiological factors and therapeutic measures.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • out of hospital cardiac arrest
  • during time prod from January 2007 until December 2014
  • CPR attempted

Exclusion criteria

  • Investigators excluded cases in which CPR was continued for less than five minutes, or duration of CPR was missing, as the outcome in this early period is not affected by the CPR mode.
  • Children aged less than 18 years and patients of unknown age were also excluded as the devices are not approved for resuscitation on children.
  • An active compression-decompression (ACD) is a hand-held suction device, to compress and actively decompress the chest after each compression.
  • Investigators also excluded cases where ACD CPR was used, because it constitutes a different technology.
  • Cases due to trauma were excluded as application of mechanical CPR devices may be limited due in traumatic events.
  • Cases where data on ROSC and/or CPR mode was missing were also excluded.

Treatment and study plan

mechanical chest compression device

Device

Primary outcomes

  1. return of spontaneous circulation

    Time frame: sustained ROSC at any time latest after 24 hours

    sustained return of spontaneous circulation at any time during CPR

Sponsors and collaborators

Lead sponsor

German Resuscitation Registry

Other

Registry information

Important dates

Study start
2007
Primary completion
2014
Study completion
2014
First posted
Oct 13, 2016
Registry last updated
Oct 13, 2016

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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