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Completed

NCT Number: NCT06945991

Application and Effect Evaluation of Integrated Nursing and Medical Management in Pediatric Lobar Pneumonia

Integrated nursing and medical management significantly improves clinical symptoms and pulmonary function in children with lobar pneumonia, shortens hospitalization duration, reduces complication rates, and enhances caregiver satisfaction. These findings support its broad clinical applicability and value.

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Key information

Conditions

Pediatrics Behavior Infections Inflammatory Markers Lobar Pneumonia Lung Diseases Personal Satisfaction Pneumonia Respiratory Tract Diseases Respiratory Tract Infections Satisfaction

Age range

1 year–12 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Hebei Children's Hospital

Shijiazhuang, 050000, China

About this study

This study aims to evaluate the clinical efficacy of integrated nursing and medical management in the treatment of pediatric lobar pneumonia. Specifically, it assesses its impact on symptom relief, pulmonary function recovery, inflammatory response control, duration of hospitalization, and caregiver satisfaction. Fifty pediatric patients diagnosed with lobar pneumonia and admitted to our hospital between January and December 2023 were selected and randomly assigned to either the observation group or the control group (n = 25 each) using a random number table. The control group received routine nursing care, while the observation group was additionally managed with an integrated nursing and medical approach. The two groups were compared in terms of duration of fever, cough, pulmonary rales, antibiotic treatment, length of hospital stay, pulmonary function parameters (FEV₁, FVC, FEV₁/FVC), inflammatory markers (CRP, WBC, PCT, LDH), overall treatment efficacy, caregiver satisfaction, and incidence of adverse events.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • (1) Met the diagnostic criteria for lobar pneumonia, presenting with symptoms such as fever, cough, and pulmonary rales, and confirmed by laboratory tests and chest X-ray;
  • (2) Aged between 1 and 12 years;
  • (3) Informed consent was obtained from the child's legal guardians.

Exclusion criteria

  • (1)Presence of other concurrent respiratory diseases;
  • (2) Congenital or acquired airway malformations, or airway foreign bodies;
  • (3) Impaired hepatic or renal function;
  • (4) Presence of other systemic diseases;
  • (5) Cognitive impairment.

Treatment and study plan

observation group

Other

the observation group was additionally managed with an integrated nursing and medical approach.

Control Group

Other

The control group received routine nursing care

Primary outcomes

  1. Time to Clinical Resolution of Symptoms

    Time frame: From admission until discharge (up to 14 days).

    Duration (in days) from hospital admission until resolution of three key symptoms: fever (axillary temperature <37.3°C for 24h), cough (absence of cough for 48h), and pulmonary rales (absence on auscultation). Assessed daily by blinded clinicians.

Secondary outcomes

  1. Change in Pulmonary Function (FEV₁, FVC, FEV₁/FVC)

    Time frame: Baseline (T0) and discharge (T1; up to 14 days).

    Absolute change in spirometry-measured FEV₁ (L), FVC (L), and FEV₁/FVC ratio (%) from admission to discharge. Assessed using standardized spirometry protocols.

  2. Reduction in Inflammatory Markers (CRP, PCT, WBC, LDH)

    Time frame: Baseline (T0) and discharge (T1; up to 14 days).

    Percent reduction in serum CRP (mg/L), PCT (ng/mL), WBC (×10⁹/L), and LDH (U/L) levels from admission to discharge.

  3. Length of Hospital Stay

    Time frame: Up to 14 days.

    Total days from admission to discharge, documented from electronic health records.

  4. Parental Satisfaction Rate

    Time frame: At discharge (T1; up to 14 days).

    Proportion of caregivers reporting "very satisfied" or "satisfied" on a 4-point Likert scale (very satisfied/satisfied/neutral/dissatisfied) at discharge.

Other outcomes

  1. Incidence of Complications

    Time frame: From admission to discharge (up to 14 days).

    Proportion of patients experiencing adverse events (e.g., hemoptysis, pneumothorax, bronchospasm) during hospitalization, verified by imaging/lab reports.

  2. Antibiotic Usage Duration

    Time frame: From admission to discontinuation (up to 14 days).

    Total days of intravenous/oral antibiotic therapy, recorded from medication logs.

  3. Adherence to Rehabilitation Protocols

    Time frame: Daily during hospitalization (up to 14 days).

    Compliance with respiratory exercises (e.g., % of scheduled postural drainage sessions completed), tracked via nursing logs.

Sponsors and collaborators

Lead sponsor

Children's Hospital of Hebei Province

Other

Registry information

Important dates

Study start
2023
Primary completion
2024
Study completion
2024
First posted
Apr 27, 2025
Registry last updated
Apr 27, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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