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OpenTrials
Completed

NCT Number: NCT04709120

Analysis of Health Status of Сomorbid Adult COVID-19 Patients Hospitalised in Second Wave of SARS-CoV-2 Infection

Comparison of COVID-19 disease course in hospitalized patients infected by SARS-CoV-2 in first and second waves of the novel coronavirus infection

Completed

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Key information

Conditions

Covid19 Arrhythmias, Cardiac Atrial Fibrillation CKD COPD COVID-19 Cardiovascular Diseases Chronic Disease Comorbidities and Coexisting Conditions Coronaviridae Infections Coronavirus Infections DVT Death Diabetes Diabetes Mellitus Disease Attributes Endocrine System Diseases Glucose Metabolism Disorders Heart Diseases Infections Lung Diseases Lung Diseases, Obstructive Metabolic Diseases Nidovirales Infections Nutritional and Metabolic Diseases Pathologic Processes Pathological Conditions, Signs and Symptoms Pneumonia Pneumonia, Viral Pulmonary Disease, Chronic Obstructive RNA Virus Infections Respiratory Tract Diseases Respiratory Tract Infections Risk Factor, Cardiovascular Virus Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Eurasian Association of Therapists

Moscow, 101000, Russia

About this study

Non-commercial depersonalized multi-centered registry study on analysis of chronic non-infectious diseases dynamics after SARS-CoV-2 in first and second waves of the novel coronavirus infection in cohort of Russian adult patients.

Retrospective analysis of medical histories and outcomes in adults with pre-existing conditions after SARS-CoV-2 infection. Comorbidities worsening risk factors measuring through evaluation of range of indicators such as dynamics of diabetes, CKD, COPD, bronchial astma, incidence of hypertonic crises, vascular events and others.

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Suspected or confirmed COVID-19 (according to results of swab-test, antibody test, computed tomography or radiography image)

Exclusion criteria

  • Unwillingness to participate in the study;
  • Age under 18.

Treatment and study plan

Primary outcomes

  1. death

    Time frame: 4 weeks

    death for any reason

Secondary outcomes

  1. Number of cases of Acute Kidney Injury depending on Coexisting Conditions

    Time frame: 4 weeks

    Number of cases of Acute Kidney Injury depending on Coexisting Conditions

  2. Number of cases of Myocarditis and Acute Coronary Events depending on Coexisting Conditions

    Time frame: 4 weeks

    Number of cases of Myocarditis and Acute Coronary Events depending on Coexisting Conditions

  3. Number of cases of Cytokine Storm depending on Coexisting Conditions

    Time frame: 4 weeks

    Number of cases of Cytokine Storm depending on Coexisting Conditions

  4. Number of thrombotic and thromboembolic complications of COVID-19 depending on Coexisting Conditions

    Time frame: 4 weeks

    Number of thrombotic and thromboembolic complications of COVID-19 depending on Coexisting Conditions

  5. Decline in GFR excluding Acute Kidney Injury by the time of discharge depending on Coexisting Conditions

    Time frame: 4 weeks

    Decline in GFR excluding Acute Kidney Injury by the time of discharge depending on Coexisting Conditions

  6. Rate of cases of health status worsening occured during hospitalisation

    Time frame: 4 weeks

    Rate of cases of health status worsening occured during hospitalisation

Sponsors and collaborators

Lead sponsor

Eurasian Association of Therapists

Other

Registry information

Acronym: ACTIV-2

Important dates

Study start
2020
Primary completion
2021
Study completion
2021
First posted
Jan 14, 2021
Registry last updated
Sep 8, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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