Tanta University
Tanta, ElGharbia, 31527, Egypt
NCT Number: NCT06331143
The aim of this study is to compare the analgesic efficacy of mid-transverse process to pleura (MTP) block and intrathecal morphine in idiopathic scoliosis patients undergoing posterior spinal fusion surgery.
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Notify Me18 year and older
All sexes
Interventional
Not applicable
Tanta, ElGharbia, 31527, Egypt
The postoperative period for idiopathic scoliosis patients undergoing posterior spinal fusion (PSF) is fraught with challenges, including adequate postoperative pain control and prolonged hospitalization.
Intrathecal opioids have been used to manage postoperative pain in pediatric patients for a wide variety of surgeries , including adolescent and adult PSF. Multimodal analgesic (MMA) regimens using several drugs and techniques are considered to be necessary for postoperative pain relief.
The mid-transverse process to pleura (MTP) block was first described as a modified paravertebral block in 2017. The local anesthetics (LAs) are administered between the transverse process and the pleura. This results in a LA spread to the dorsal and ventral rami in the paravertebral space through the fenestrations in the superior costotransverse ligament at the level of injection, and frequently to adjacent levels.
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
Patients will receive MTP block after induction of anesthesia.
Patients will receive intrathecal morphine in a dose of 12 μg/kg (max 1000 μg) immediately after induction of anesthesia.
Time frame: 24 hours postoperative
Degree of pain will be assessed by the Visual Analogue Scale (VAS). VAS (0 represents "no pain" while 10 represents "the worst pain imaginable").
It will be assessed at 0, 4, 8, 12, 18 and 24h postoperatively.
Time frame: Till the end of surgery.
Heart rate will be recorded preoperative, before performing of block, and every 15 min till the end of surgery.
Time frame: Till the end of surgery.
Mean arterial pressure will be recorded preoperative, before performing of block, and every 15 min till the end of surgery.
Time frame: 24 hours postoperative.
Degree of patient satisfaction will be assessed on a 5-point Likert scale patient satisfaction (1, extremely dissatisfied; 2, unsatisfied; 3, neutral; 4, satisfied; 5, extremely satisfied).
It will be assessed 24 hours after surgery.
Time frame: 24 hours postoperative.
Complications such as bradycardia, hypotension, nausea, vomiting, Pruritis, respiratory depression, or any other complication.
Tanta University
Other
Comparison of Analgesic Efficacy of Mid-Transverse Process to Pleura (MTP) Block and Intrathecal Morphine in Idiopathic Scoliosis Patients Undergoing Posterior Spinal Fusion: A Randomized Clinical Trial
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View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
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