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Completed

NCT Number: NCT02255630

Anaerobic Power and Salbutamol

Athletes using inhaled β2-adrenoreceptor agonists (IBAs) win a disproportionate number of medals. However, most previous research has shown that β2 agonists do not improve exercise performance in either asthmatic or non-asthmatic athletes. Although the majority of these studies do not show an ergogenic effect, the small number of studies with extended exercise bouts (~60 minutes) do show an advantage. The investigators believe that a controlled yet sport-specific exercise protocol will elucidate this ergogenic effect. Because IBAs may have different effects on these two groups of athletes, the investigators will measure exercise performance in both female and male elite cyclists. The investigators hypothesize that athletes will perform better during a combination steady-state/sprint exercise task following salbutamol administration.

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Key information

Conditions

Ergogenic Athletic Performance

Age range

19 year–40 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

University of British Columbia, Environmental Physiology Laboratory

Vancouver, British Columbia, V6T 1Z1, Canada

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • maximal oxygen consumption of ≥60 and ≥55 mL⋅kg-1⋅min-1 or ≥5⋅L⋅min-1 and ≥4⋅L⋅min-1 for men and women

Exclusion criteria

  • pregnant women
  • any history of uncontrolled respiratory or cardiac disease
  • smokers
  • diabetics

Treatment and study plan

cycling exercise

Other

Primary outcomes

  1. Peak Power Output

    Time frame: peak power output of the final 30 seconds of the cycling bout will be assessed.

Sponsors and collaborators

Lead sponsor

University of British Columbia

Other

Collaborators

  • Natural Sciences and Engineering Research Council, Canada

Registry information

Official study title

The Effects of High-dose Salbutamol on Anaerobic Cycling Power

Important dates

Study start
2015
Primary completion
2015
Study completion
2016
First posted
Oct 2, 2014
Registry last updated
Nov 10, 2016

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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