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Completed

NCT Number: NCT07114341

Effect of Lyophilized Cornelian Cherry on Anaerobic Performance in Young Football Players

The goal of this clinical trial is to learn if a lyophilized Cornelian Cherry supplement works to improve anaerobic performance and reduce fatigue in young football players (U14-U19 age group).

The main questions it aims to answer are:

* Does taking a lyophilized Cornelian Cherry supplement improve participants' anaerobic performance as measured by the Running-based Anaerobic Sprint Test (RAST)? * Does the supplement reduce participants' levels of fatigue after strenuous exercise?

Researchers will measure participants' performance and fatigue levels before the study begins and compare them to the levels measured after 1 week of taking the cranberry supplement. This will help determine the effect of the supplement.

Participants will:

* Take 30 grams of lyophilized Cornelian Cherry powder every day for 1 week. * Visit the study center at the beginning and at the end of the 1-week period for checkups and tests. * Undergo anthropometric measurements (such as height, weight, and body composition) at the start of the study. * Perform a Running-based Anaerobic Sprint Test (RAST) and a fatigue test at the start and end of the study.

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Key information

Conditions

Sport Nutrition Ergogenic Athletic Performance Ergogenic Support Sports Nutritional Sciences Sports Performance in Children

Age range

14 year–19 year

Sex eligibility

Male

Study type

Interventional

Phase

Not applicable

Primary location

Istanbul Bilgi University

Istanbul, Turkey (Türkiye)

About this study

A balanced diet plays a role in preventing injuries, improving athletic performance, and accelerating post-exercise recovery in adolescents who engage in physical activity. The physiological response to exercise can vary depending on the duration, intensity, and frequency of exercise, as well as environmental conditions. Excessive reactive oxygen species (ROS) production triggered by high-intensity exercise or other stress factors in athletes can lead to oxidative stress and subsequent tissue damage by weakening the antioxidant defense system. Therefore, athletes may need to maintain increased ROS scavenging activity. Additionally, physical exercise can lead to injuries in skeletal muscle tissue, leading to decreased performance. Therefore, strategies to manage exercise-related injuries and post-exercise inflammatory processes may contribute to accelerating exercise adaptation and recovery. Recently, there has been increasing support for the possibility of improving exercise performance through supplementation with fruit-derived polyphenols. Polyphenols are secondary metabolites abundant in plant foods and are divided into four main groups: lignans, stilbenes, and flavonoids. Anthocyanins, a subclass of flavonoids, are found in red, purple, and blue vegetables and fruits. Anthocyanins are known for their antioxidant and anti-inflammatory properties, and therefore, they are thought to prevent adverse physiological effects such as fatigue and post-exercise inflammation, which can potentially occur during exercise. The potential mechanism of action is thought to be related to antioxidant and vascular effects. Turkey is among the countries where cornelian cherries, another fruit with high biological value due to their anthocyanin and other phenolic compounds, are cultivated. Randomized controlled trials have examined the effectiveness of freeze-dried cornelian cherry supplements in various disease groups. Studies have observed positive effects on lipid profiles, as well as parameters related to body mass index (BMI), body weight, waist and hip circumference, and insulin resistance. Another randomized controlled trial has indicated that cornelian cherry supplementation may be effective in accelerating post-exercise recovery in athletes. While the literature has evaluated the effects of various forms of supplementation with fruits high in anthocyanins on sports performance, studies examining anaerobic power and capacity with cornelian cherry supplementation in adolescent athletes are limited. Therefore, the purpose of this study was to evaluate the effects of freeze-dried cornelian cherry fruit on anaerobic performance in adolescent soccer players.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • 13-18 ages of adolescent football

Exclusion criteria

  • Disease diagnosis or history,
  • Regular medication use,
  • Regular nutritional supplement use,
  • Being under 14 years of age,
  • Being over 19 years of age.

Treatment and study plan

Cranberry Intervention

Other

30 grams of lyophilized cranberry containing 1187 mg/100 g anthocyanins were given for 7 days.

Primary outcomes

  1. Running-Based Anaerobic Sprint Test (RAST) - Performance Test

    Time frame: From enrollment to the end of study at 1 week

    The RAST is a test consisting of six 35-meter sprints at maximum speed, with a 10-second rest interval between each sprint. In this test, power is calculated for each sprint using body mass and the resulting performance data (Power = (Total body mass x Distance2) / Time3). The highest recorded number is called maximum power; the lowest number is called minimum power; and the sum of the six sprints divided by six is called average power. Muscle fatigue is assessed using the Fatigue Index (Maximum Power - Minimum Power) / Sum of the 6 sprint times). A lower value indicates that athletes have better muscular ability to maintain their performance without fatigue.

Secondary outcomes

  1. Anthropometric Measurements - Body weight (kg)

    Time frame: From enrollment to the end of study at 1 week

    At the beginning and end of the study, body weights (kg) measured using a bioelectrical impedance (BIA) device with a sensitivity of 50 grams in accordance with the measurement standards.

  2. Anthropometric Measurements - Height

    Time frame: 1 week

    Height (cm) measured with a stadiometer in the Frankfort plane, standing and with the head upright.

  3. Body Mass Index

    Time frame: From enrollment to the end of study at 1 week

    The body mass index (BMI) of the participants was calculated according to the body weight (kg) / height (m)2 formula.

  4. Anthropometric Measurements - Fat Mass

    Time frame: From enrollment to the end of study at 1 week

    At the beginning and end of the study, body fat mass (kg) analysis was performed using a bioelectrical impedance (BIA) device, paying attention to measurement standards.

  5. Anthropometric Measurements - Fat ratio calculation

    Time frame: From enrollment to the end of study at 1 week

    At the beginning and end of the study, body composition analyses was performed using a bioelectrical impedance (BIA) device with measurement standards. According to the BIA analysis, fat percentage (%) will be calculated as the ratio of total body fat weight to total body weight.

  6. Anthropometric Measurements - Fat-free mass

    Time frame: From enrollment to the end of study at 1 week

    At the beginning and end of the study, fat-free mass (kg) was analyzed using a bioelectrical impedance (BIA) device, paying attention to measurement standards.

  7. Anthropometric Measurements - Muscle mass

    Time frame: From enrollment to the end of study at 1 week

    At the beginning and end of the study, lean muscle mass (kg) was analyzed using a bioelectrical impedance (BIA) device, paying attention to measurement standards.

  8. Anthropometric Measurements - Total body water

    Time frame: From enrollment to the end of study at 1 week

    At the beginning and end of the study, total body water (kg) was analyzed using a bioelectrical impedance (BIA) device, paying attention to measurement standards.

  9. Food Consumption Record - Energy

    Time frame: 1 day

    The food consumption record was taken to evaluate the nutritional status of the participants. Food consumption records were evaluated in the BeBIS (Nutrition Information System) program and the daily energy (kcal) intake will be calculated.

  10. Food Consumption Record

    Time frame: 1 day

    The food consumption record were taken to evaluate the nutritional status of the participants. Food consumption records were evaluated in the BeBIS (Nutrition Information System) program and the daily carbohydrate (g), protein (g), fat (g), saturated fat (g), monounsaturated fatty acid (g), polyunsaturated fatty acid (g), omega-3 fatty acids (g), omega-6 fatty acids (g), and fiber (g) intake were calculated.

  11. Food Consumption Record

    Time frame: 1 day

    The food consumption record was taken to evaluate the nutritional status of the participants. Food consumption records were evaluated in the BeBIS (Nutrition Information System) program and the daily vitamin A (µg), vitamin D (µg), vitamin K (µg), folate (µg), and vitamin B12 (µg) intake were calculated.

  12. Food Consumption Record

    Time frame: 1 day

    The food consumption record was taken to evaluate the nutritional status of the participants. Food consumption records were evaluated in the BeBIS (Nutrition Information System) program and the daily vitamin E (mg), thiamine (mg), riboflavine (mg), niacin (mg), vitamine B5 (mg), vitamin B6 (mg), vitamin C, sodium (mg), potassium (mg), calcium (mg), magnesium (mg), phosphor (mg), iron (mg), zinc (mg), copper (mg), cholesterol (mg) intake were calculated.

Sponsors and collaborators

Lead sponsor

Istanbul Bilgi University

Other

Registry information

Important dates

Study start
2025
Primary completion
2025
Study completion
2025
First posted
Aug 11, 2025
Registry last updated
Sep 8, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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