An Evaluation of a Social Network Intervention for Primary and Secondary Prevention of Opioid Overdoses

The specific aims of the study are:

• Conduct a pilot of an HIV/HCV/overdose prevention and care intervention for people who use opiates.
• Evaluate the feasibility of collecting donated drug preparation containers (i.e., cookers) to assess the presence of fentanyl, HCV, and HIV.
• Conduct a randomized controlled trial to assess efficacy of the experimental Peer Mentor condition on (a) overdose prevention and care education to drug network members, (b) naloxone availability, and (c) drug treatment readiness and entry.

There are two types of participants: Index participants and network participants. Both type of participant will currently used opiates. Participants will take part in a baseline visit and up to 3 follow-up visits. Index participants will be randomized into the intervention or control arm of the study.

Inclusion criteria

for Index participants:

• self-reported use of opiates including heroin, fentanyl, or prescription opiates to get high at least 2 times in the last two weeks;
• willing to invite a network member who uses drugs to the study;
• ages 18-years or older;
• living in the Baltimore metropolitan region, and
• not previously enrolled in the study or currently enrolled in another Lighthouse study.

Inclusion criteria

for network participants:

• self-reported use of illicit injecting or non-injecting opiates at least 2 times in the last two weeks;
• sees the Index participant 2 or more times in the past week;
• ages 18 years or older; and
• living in the Baltimore metropolitan region.

Exclusion criteria

• Index participants may not take part in the study as a Network participant.
• Network participants may not take part in the study as an Index participant.