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NCT Number: NCT07079917

Alveolar Ridge Augmentation Using Minimally Invasive Subperiosteal Tunneling With Xenogenic Bone Graft and PRF

surgical horizontal augmentation for maxillary alveolar ridge using minimally invasive subperiosteal tunneling in comparison to conventional surgical technique

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Key information

Conditions

Alveolar Bone Loss Bone Diseases Bone Resorption Mouth Diseases Musculoskeletal Diseases Periodontal Atrophy Periodontal Diseases Stomatognathic Diseases

Age range

18 year–60 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Fayoum University

Al Fayyum, Egypt

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Adults over 18 years old seeking an implant-supported restoration with deficient horizontal posterior maxillary alveolar ridge, at area of one or two missed teeth of less than 5 mm buccolingual width.
  • Minimum vertical height of 8 mm.
  • Gingival tissue of healthy adequate keratinization, more than 2mm.

Exclusion criteria

  • The presence of uncontrolled diabetes or any other systemic condition which may complicate the surgical procedure or interfere with bone healing
  • Radiotherapy to the head and neck region
  • Chemotherapy within the last 12 months
  • Uncontrolled periodontitis
  • Smoking
  • Bisphosphonate therapy
  • Pregnancy
  • Presence of periapical infection or lesion

Treatment and study plan

subperiosteal tunneling for horizontal alveolar ridge augmentation

Procedure

subperiosteal dissection through horizontal incision only

conventional alveolar ridge augmentation

Procedure

horizontal alveolar ridge augmentation through trapezoidal flap

Primary outcomes

  1. Maxillary alveolar bone width

    Time frame: 6 months

    increase of the alveolar bone buccolingually for horizontal ridge augmentation

Sponsors and collaborators

Lead sponsor

Fayoum University

Other

Registry information

Official study title

Alveolar Ridge Augmentation Using Minimally Invasive Subperiosteal Tunneling With Xenogenic Bone Graft and Platelet-Rich Fibrin: Randomized Controlled Trial

Acronym: MISTT

Important dates

Study start
2025
Primary completion
2025
Study completion
2026
First posted
Jul 23, 2025
Registry last updated
Jul 23, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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