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NCT Number: NCT07520526

Immediate Implant Placement Using Socket Shield With CGF

This prospective case series study aims to clinically and radiographically evaluate the effectiveness of the socket shield technique combined with concentrated growth factors (CGF) in immediate implant placement in the esthetic zone. Outcomes will include crestal bone level changes assessed by CBCT and implant stability measured using Osstell.

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Cairo University

Cairo, Cairo Governorate, 11765, Egypt

About this study

This prospective case series study will be conducted to evaluate clinically and radiographically the effectiveness of the socket shield technique combined with concentrated growth factors (CGF) during immediate implant placement in the esthetic zone.

Eligible patients requiring extraction and immediate implant placement in the maxillary anterior or premolar region will be included. Following atraumatic extraction, partial extraction therapy using the socket shield technique will be performed, leaving the buccal root fragment in place. Implant osteotomy and placement will then be carried out according to manufacturer instructions.

Autologous concentrated growth factors will be prepared from the patient's blood using a CGF centrifugation protocol. The CGF gel will be packed into the jumping gap between the implant and socket wall to promote bone regeneration and healing.

Clinical and radiographic evaluation will be performed using CBCT at baseline, 2 weeks, and 6 months postoperatively. The primary outcome will be crestal bone level changes measured radiographically, while the secondary outcome will include implant stability assessed using Osstell measurements (ISQ values).

Seven participants will be recruited in this case series. Follow-up will be conducted to evaluate healing, bone remodeling, and implant stability.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age ≥18 years old. (Younis, W., & El-Rashidy, A. 2020).
  • Both male and female patients.
  • Maxillary, anterior and premolar segment.

Exclusion criteria

  • A medical history that contraindicates oral surgical treatment such as (uncontrolled/untreated diabetes mellitus, immuno-compromised status, radio or chemotherapy of the oral and maxillofacial region, treatment with oral and/or intravenous bisphosphonates).
  • Presence of active or untreated periodontal disease.
  • Vertical root fractures involving the buccal aspect.
  • Tooth /teeth with horizontal fractures below bone level.
  • Tooth /teeth with external or internal resorption.
  • Patients with destructive oral habits such as smoking, chewing tobacco, bruxism, etcetera.

Treatment and study plan

Immediate implant placement with Socket Shield Technique and CGF

Procedure

Partial extraction therapy using the socket shield technique followed by immediate implant placement. Concentrated growth factors prepared from autologous blood will be packed in the jumping gap to enhance bone regeneration and healing.

Other names: Socket Shield technique, Concentrated Growth Factors, Immediate implant placement

Primary outcomes

  1. Crestal bone level

    Time frame: 2 weeks and 6 months post-operatively

    Radiographic evaluation of crestal bone level changes around the implant using CBCT, measured in millimeters (mm).

Secondary outcomes

  1. Implant stability

    Time frame: Immediately after implant placement and at 6 months

    Implant stability will be assessed using resonance frequency analysis with the Osstell device and recorded as Implant Stability Quotient (ISQ). ISQ values range from 1 to 100, where higher values indicate greater implant stability and a better outcome.

Study contacts

Contact information is provided by the study sponsor or research team.

Areej Khalid Rasheid, bachelors

CONTACT

[email protected]

+201033903216 ext. +201033903216

Sponsors and collaborators

Lead sponsor

Cairo University

Other

Registry information

Official study title

Clinical and Radiographic Evaluation of Concentrated Growth Factors With Simultaneous Immediate Implant Placement in Socket Shield Technique

Acronym: CGF

Important dates

Study start
2026
Primary completion
2026
Study completion
2026
First posted
Apr 9, 2026
Registry last updated
Apr 13, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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