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OpenTrials
Completed

NCT Number: NCT05791123

Alveolar Ridge Augmentation Following Tooth Extraction Using Bovine Xenograft With Platelet Rich Fibrin Membrane

fourteen patients requiring extraction of one posterior tooth with lost buccal bone (>50%) confirmed preoperatively by Cone-beam computed tomography (CBCT) scans. Extraction sockets were filled with minced PRF clots mixed with the bovine xenograft and covered by PRF membranes to seal the extraction sockets. (CBCT) scans, performed before tooth extraction and after 6 months, were used to assess vertical and horizontal bone changes.

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Key information

Conditions

Bone Regeneration

Age range

20 year–60 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Future University in Egypt

Cairo, Egypt

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients required implant treatment after tooth extraction
  • Age group ranged from 20-60 years old.
  • Patients could undergo the treatment under local anesthesia.
  • Loss of buccal bone (>50%) confirmed by preoperative cone beam computed tomography (CBCT).
  • Presence of other socket walls; mesial, distal and lingual walls.
  • Tooth needed to be extracted in upper or lower posterior regions

Exclusion criteria

  • Uncontrolled diabetic diseases.
  • Uncontrolled hypertension, or hepatic and renal disorders.
  • Any systemic diseases associated with bone metabolism.

Treatment and study plan

a bone graft mixed with PRF & covered by PRF membrane in fresh extraction socket

Procedure

Extraction sockets were filled with minced PRF clots mixed with the bovine xenograft and covered by PRF membranes to seal the extraction sockets.

Primary outcomes

  1. the change in alveolar bone width and height in mm using CBCT scans.

    Time frame: 6 months

    Cone Beam Computed Tomography were taken for each patients before tooth extraction and after 6 months, which were used to assess alveolar ridge changes in width and length in mm.

Sponsors and collaborators

Lead sponsor

Future University in Egypt

Other

Registry information

Important dates

Study start
2018
Primary completion
2023
Study completion
2023
First posted
Mar 30, 2023
Registry last updated
Mar 30, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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