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Completed

NCT Number: NCT06657417

A.I. Supported Laryngoscopy and Endotracheal Intubation: a Manikin Study

LarynGuide is a newly developed AI-supported software for video laryngoscopy that supports the user through correct placement of endotracheal tube by means of audio-visual signals and warning of incorrect or potentially dangerous handling. This prospective study assesses the performance of tracheal intubation using video laryngoscopy with larynGuide AI overlay as compared to standard video larnygoscopy an simulation setting.

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Key information

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Schulthess Klinik

Zurich, 8008, Switzerland

About this study

Tracheal intubation is a core competence in anesthesia and emergency medicine. This complex medical procedure aims to preserve gas exchange in the lungs. Vital for that is a secured and patent airway as soon as spontaneous ventilation ceases under general anesthesia or in life-threatening conditions like (e.g, respiratory insufficiency or resuscitation). Failure in securing an airway can result in hypoxemia, leading to neurologic damage, cardiovascular complications, and death. Complex anatomic structures or abnormalities of the upper airway, as well as airway trauma, bear the risk of failed intubation and inability to ventilate the lungs, which furthermore may result in ventilation and oxygenation failure. Tracheal intubation's success highly depends on user experience and skills. Literature reports unexpected difficult intubations ranging from 5 to 10%, mostly corresponding to a Cormack/Lehane grade 3 or 4.4-7. Besides classic direct laryngoscopes and flexible optic endoscopes, video laryngoscopes with high-resolution video cameras placed at the tip of the devices facilitate tracheal intubation. Video laryngoscopy seems superior in normal and difficult intubation, as it improves the first-attempt success rate.

Complication rates and upper airway trauma after direct laryngoscopy with a Macintosh type blade in patients with normal airway have been reported up to 7%15. Video laryngoscopy reduces that relative high incidence Upper airway trauma is increased when physical force is used during laryngoscopy to improve limited view on the glottis16 or if more than two intubation attempts are needed. The newly developed larynGuide software is an artificially intelligent video laryngoscope monitoring system which provides information to the user on visible anatomy, next steps to advance the oro-tracheal intubation to completion, and to advise on un-safe or incorrect maneuvers & interventions. As soon as the device places the scope into the trachea the provider slides the tracheal tube over the scope into the proper place of the trachea as usually done during flexible scope intubation.

Aimof this study is to determine the effects larynGuide has on tracheal intubation performance compared with standard of care video laryngoscopy.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

  • Volunteer medical professionals
  • Experienced: consultant anaesthetists, resident anaesthetists and certified nurse
  • Inexperienced: junior doctors (other than anaesthetists), clinical year medical students, nurses and paramedics

Treatment and study plan

Video Laryngoscopy

Device

Standard video laryngoscopy before video laryngoscopy with additional larynGuide overlay

Video larnygoscopy

Device

Video laryngoscopy with additional larynGuide overlay before standard video laryngoscopy

Primary outcomes

  1. Rate of first-attempt tracheal intubation success

    Time frame: 2 minutes

    12 single attempts per participant

Secondary outcomes

  1. Time to intubation

    Time frame: 2 minutes

    12 single attempts per participant

  2. Rate of total intubation success

    Time frame: 2 minutes

    12 single attempts per participant

  3. Global Rating Scale of Procedural Performance

    Time frame: 2 minutes

    instrument handling, flow and knowledge of procedure for each intubation on a grade scale from 1 to 5; 12 single time points per participant

  4. Percentage of dental damage incidence

    Time frame: 2 minutes

    12 single attempts per participant

Sponsors and collaborators

Lead sponsor

Schulthess Klinik

Other

Registry information

Acronym: aiTN

Important dates

Study start
2024
Primary completion
2024
Study completion
2024
First posted
Oct 24, 2024
Registry last updated
Oct 24, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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