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Enrolling by Invitation

NCT Number: NCT06931782

AI in Respiratory Disease Prevention, Diagnosis, and Triage

This study will evaluate the impact of using the GPT-4o compared to traditional online tools in the field of respiratory disease prevention, focusing on the dissemination of knowledge and behavior changes among the general public. We will explore the effectiveness of GPT-4o in enhancing public awareness and management capabilities regarding respiratory diseases and promoting appropriate preventive behaviors.

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Key information

Age range

18 year–75 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

the First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong 510120

Guangzhou, Guangdong, 510120, China

About this study

Artificial intelligence (AI) technologies, particularly advanced large language models like GPT-4o developed by OpenAI, hold immense potential in enhancing public health education and preventive behaviors. Although GPT-4o was not specifically designed for respiratory disease prevention, it has shown promising prospects in numerous healthcare-related applications, such as providing health information, responding to public inquiries, and supporting health education efforts. However, its effectiveness in improving public awareness and management capabilities regarding respiratory diseases remains to be further explored.

Understanding and managing respiratory diseases involve complex processes, including symptom recognition, application of preventive knowledge, and informed decision-making. Integrating AI tools like GPT-4o into public health education could potentially enhance knowledge dissemination, reduce misinformation, and encourage appropriate preventive behaviors among the general population. Nevertheless, GPT-4o has not been specifically validated for respiratory disease prevention and carries the risk of generating misleading or inaccurate information, which could confuse users. Improper use of such tools may fail to raise awareness and could even lead to counterproductive behaviors. Therefore, studying how large language models like GPT-4o can effectively support public education and behavior change in this context is of critical importance.

In this study, participants will be randomly divided into two groups: one group will have access to Fine-turned GPT-4o, while the other will rely solely on traditional online tools. They will be presented with scenarios related to respiratory diseases and asked to explain their identification of high-risk factors, understanding of diagnoses, and proposed triage actions for each scenario. Each scenario was developed by a panel of three experts in respiratory health, who also established standardized answers. Responses will be evaluated by two independent groups of reviewers unaware of the participants' group assignments. These experts independently created initial scoring criteria and resolved discrepancies through multiple rounds of discussion to ensure consistency and accuracy.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • No medical background
  • Aged from 18 to 75 years old

Exclusion criteria

  • Had a medical background
  • Exceeds the age criteria
  • Failed to comply with the survey requirements

Treatment and study plan

AI

Other

GPT-4o fine-tuned with the Lungdiag database

Primary outcomes

  1. the accuracy of participants in answering questions related to triage, diagnosis, and risk factor identification of respiratory diseases using artificial intelligence versus internet-based information retrieval assessed by questionnaire survey

    Time frame: From enrollment to the end of test at 1 hour.

Secondary outcomes

  1. the accuracy of different subgroups in answering questions related to triage, diagnosis, and risk factor identification of respiratory diseases using artificial intelligence versus internet-based information retrieval assessed by questionnaire survey

    Time frame: From enrollment to the end of test at 1 hour.

  2. Time (in seconds) participants spend per questionnaire between the two study arms.

    Time frame: From enrollment to the end of test at 1 hour.

Sponsors and collaborators

Lead sponsor

The First Affiliated Hospital of Guangzhou Medical University

Other

Registry information

Official study title

Effectiveness of Artificial Intelligence (AI) in the Prevention, Diagnosis, and Triage of Respiratory Diseases: A Multicenter, Randomized Controlled Study

Important dates

Study start
2025
Primary completion
2025
Study completion
2025
First posted
Apr 17, 2025
Registry last updated
Apr 17, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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